Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
JR Corte, W Yang, T Fang, Y Wang, H Osuna… - Bioorganic & Medicinal …, 2017 - Elsevier
Optimization of macrocyclic inhibitors of FXIa is described which focused on modifications to
both the macrocyclic linker and the P1 group. Increases in potency were discovered through …
both the macrocyclic linker and the P1 group. Increases in potency were discovered through …
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
JR Corte, W Yang, T Fang, Y Wang… - Bioorganic & …, 2017 - pubmed.ncbi.nlm.nih.gov
Optimization of macrocyclic inhibitors of FXIa is described which focused on modifications to
both the macrocyclic linker and the P1 group. Increases in potency were discovered through …
both the macrocyclic linker and the P1 group. Increases in potency were discovered through …
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency.
JR Corte, W Yang, T Fang, Y Wang… - Bioorganic & …, 2017 - europepmc.org
Optimization of macrocyclic inhibitors of FXIa is described which focused on modifications to
both the macrocyclic linker and the P1 group. Increases in potency were discovered through …
both the macrocyclic linker and the P1 group. Increases in potency were discovered through …