[HTML][HTML] BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors

A Tálas, DA Simon, PI Kulcsár, É Varga… - Nature …, 2021 - nature.com
Adenine and cytosine base editors (ABE, CBE) allow for precision genome engineering.
Here, Base Editor Activity Reporter (BEAR), a plasmid-based fluorescent tool is introduced …

BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors

A Tálas, DA Simon, PI Kulcsár, É Varga… - Nature …, 2021 - ideas.repec.org
Adenine and cytosine base editors (ABE, CBE) allow for precision genome engineering.
Here, Base Editor Activity Reporter (BEAR), a plasmid-based fluorescent tool is introduced …

BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors

A Tálas, DA Simon, PI Kulcsár… - Nature …, 2021 - pubmed.ncbi.nlm.nih.gov
Adenine and cytosine base editors (ABE, CBE) allow for precision genome engineering.
Here, Base Editor Activity Reporter (BEAR), a plasmid-based fluorescent tool is introduced …

BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors

A Tálas, DA Simon, PI Kulcsár, É Varga… - NATURE …, 2021 - real.mtak.hu
Results Development of the BEAR assay. We aimed to develop an easyto-perform and quick
gain-of-signal fluorescent assay to monitor base editing activity with a plasmid-based format …

BEAR reveals that increased fidelity variants can successfully reduce the mismatch-tolerance of adenine but not cytosine base editors

A Tálas, D Simon, P Kulcsár, É Varga, E Welker - 2020 - researchsquare.com
Adenine and cytosine base editors (ABE, CBE) are designed to generate single base
mutations in genes without necessarily generating DNA double-strand breaks and …

[PDF][PDF] BEAR reveals that increased fidelity variants can successfully reduce the mismatch-tolerance of adenine but not cytosine base editors

A Tálas, D Simon, P Kulcsár, É Varga, E Welker - scholar.archive.org
Adenine and cytosine base editors (ABE, CBE) are designed to generate single base
mutations in genes without necessarily generating DNA double-strand breaks and …

BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors.

A Tálas, DA Simon, PI Kulcsár, É Varga… - Nature …, 2021 - europepmc.org
Adenine and cytosine base editors (ABE, CBE) allow for precision genome engineering.
Here, Base Editor Activity Reporter (BEAR), a plasmid-based fluorescent tool is introduced …

BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors

A Tálas, DA Simon, PI Kulcsár, É Varga… - Nature …, 2021 - ui.adsabs.harvard.edu
Adenine and cytosine base editors (ABE, CBE) allow for precision genome engineering.
Here, Base Editor Activity Reporter (BEAR), a plasmid-based fluorescent tool is introduced …

BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors.

A Tálas, DA Simon, PI Kulcsár, É Varga… - Nature …, 2021 - search.ebscohost.com
Adenine and cytosine base editors (ABE, CBE) allow for precision genome engineering.
Here, Base Editor Activity Reporter (BEAR), a plasmid-based fluorescent tool is introduced …

[HTML][HTML] BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors

A Tálas, DA Simon, PI Kulcsár, É Varga… - Nature …, 2021 - ncbi.nlm.nih.gov
Adenine and cytosine base editors (ABE, CBE) allow for precision genome engineering.
Here, Base Editor Activity Reporter (BEAR), a plasmid-based fluorescent tool is introduced …