Breaking oncogene addiction: getting RTK/RAS-mutated cancers off the SOS
E Sheffels, RL Kortum - Journal of Medicinal Chemistry, 2021 - ACS Publications
In RTK/RAS-mutated cancers, therapeutic resistance is driven by rebound activation of
multiple RTKs; broad inhibition of RTK signaling can potentially delay therapeutic resistance …
multiple RTKs; broad inhibition of RTK signaling can potentially delay therapeutic resistance …
Breaking Oncogene Addiction: Getting RTK/RAS-Mutated Cancers off the SOS.
E Sheffels, RL Kortum - Journal of Medicinal Chemistry, 2021 - europepmc.org
In RTK/RAS-mutated cancers, therapeutic resistance is driven by rebound activation of
multiple RTKs; broad inhibition of RTK signaling can potentially delay therapeutic resistance …
multiple RTKs; broad inhibition of RTK signaling can potentially delay therapeutic resistance …
Breaking Oncogene Addiction: Getting RTK/RAS-Mutated Cancers off the SOS
E Sheffels, RL Kortum - Journal of medicinal chemistry, 2021 - pubmed.ncbi.nlm.nih.gov
In RTK/RAS-mutated cancers, therapeutic resistance is driven by rebound activation of
multiple RTKs; broad inhibition of RTK signaling can potentially delay therapeutic resistance …
multiple RTKs; broad inhibition of RTK signaling can potentially delay therapeutic resistance …