Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

KJ Kearney, J Butler, OM Posada… - Proceedings of the …, 2021 - National Acad Sciences
Kallikrein (PKa), generated by activation of its precursor prekallikrein (PK), plays a role in the
contact activation phase of coagulation and functions in the kallikrein-kinin system to …

Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

KJ Kearney, J Butler, OM Posada… - Proceedings of the …, 2021 - eprints.whiterose.ac.uk
Kallikrein (PKa), generated by activation of its precursor prekallikrein (PK), plays a role in the
contact activation phase of coagulation and functions in the kallikrein-kinin system to …

[HTML][HTML] Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

KJ Kearney, J Butler, OM Posada… - Proceedings of the …, 2021 - ncbi.nlm.nih.gov
Absence of FXII and FXI. To assess whether PKa could initiate thrombin generation
independently of its FXII-activating activity, thrombin generation was measured in FXII …

[PDF][PDF] Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

KJ Kearneya, J Butlera, OM Posadaa, C Wilsona… - PNAS, 2021 - academia.edu
Absence of FXII and FXI. To assess whether PKa could initiate thrombin generation
independently of its FXII-activating activity, thrombin generation was measured in FXII …

Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI.

KJ Kearney, J Butler, OM Posada, C Wilson… - Proceedings of the …, 2021 - europepmc.org
Kallikrein (PKa), generated by activation of its precursor prekallikrein (PK), plays a role in the
contact activation phase of coagulation and functions in the kallikrein-kinin system to …

Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

KJ Kearney, J Butler, OM Posada… - Proceedings of the …, 2021 - pubmed.ncbi.nlm.nih.gov
Kallikrein (PKa), generated by activation of its precursor prekallikrein (PK), plays a role in the
contact activation phase of coagulation and functions in the kallikrein-kinin system to …

Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

KJ Kearney, J Butler, OM Posada, C Wilson… - Proceedings of the …, 2021 - JSTOR
Kallikrein (PKa), generated by activation of its precursor prekallikrein (PK), plays a role in the
contact activation phase of coagulation and functions in the kallikrein-kinin system to …

Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

KJ Kearney, J Butler, OM Posada… - Proceedings of the …, 2021 - ui.adsabs.harvard.edu
Prekallikrein (PK) is a zymogen that is converted to kallikrein (PKa) by factor (F) XIIa. PK and
FXII reciprocally activate each other; the resulting FXIIa initiates activation of the coagulation …

Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI.

KJ Kearney, J Butler, OM Posada, C Wilson… - Proceedings of the …, 2021 - europepmc.org
Absence of FXII and FXI. To assess whether PKa could initiate thrombin generation
independently of its FXII-activating activity, thrombin generation was measured in FXII …