Iterative design and optimization of initially inactive proteolysis targeting chimeras (PROTACs) identify VZ185 as a potent, fast, and selective von Hippel–Lindau (VHL) …

V Zoppi, SJ Hughes, C Maniaci, A Testa… - Journal of medicinal …, 2018 - ACS Publications
Developing PROTACs to redirect the ubiquitination activity of E3 ligases and potently
degrade a target protein within cells can be a lengthy and unpredictable process, and it …

Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL) …

V Zoppi, SJ Hughes, C Maniaci… - Journal of …, 2019 - discovery.dundee.ac.uk
Developing PROTACs to redirect the ubiquitination activity of E3 ligases and potently
degrade a target protein within cells can be a lengthy and unpredictable process, and it …

Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau …

V Zoppi, SJ Hughes, C Maniaci, A Testa… - Journal of Medicinal …, 2018 - europepmc.org
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs)
Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader …

[HTML][HTML] Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel …

V Zoppi, SJ Hughes, C Maniaci, A Testa… - Journal of Medicinal …, 2019 - ncbi.nlm.nih.gov
Developing PROTACs to redirect the ubiquitination activity of E3 ligases and potently
degrade a target protein within cells can be a lengthy and unpredictable process, and it …

Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau …

V Zoppi, SJ Hughes, C Maniaci, A Testa… - Journal of Medicinal …, 2018 - eprints.ncl.ac.uk
Developing PROTACs to redirect the ubiquitination activity of E3 ligases and potently
degrade a target protein within cells can be a lengthy and unpredictable process, and it …

[引用][C] Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel …

V Zoppi, SJ Hughes, C Maniaci, A Testa… - Journal of Medicinal …, 2018 - cir.nii.ac.jp
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs)
Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader …

[PDF][PDF] Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel …

V Zoppi, SJ Hughes, C Maniaci, A Testa, T Gmaschitz… - core.ac.uk
Developing PROTACs to redirect the ubiquitination activity of E3 ligases and potently
degrade a target protein within cells can be a lengthy and unpredictable process, and it …

Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau …

V Zoppi, SJ Hughes, C Maniaci… - Journal of …, 2019 - pubmed.ncbi.nlm.nih.gov
Developing PROTACs to redirect the ubiquitination activity of E3 ligases and potently
degrade a target protein within cells can be a lengthy and unpredictable process, and it …

[PDF][PDF] Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel …

V Zoppi, SJ Hughes, C Maniaci, A Testa, T Gmaschitz… - discovery.dundee.ac.uk
Developing PROTACs to redirect the ubiquitination activity of E3 ligases and potently
degrade a target protein within cells can be a lengthy and unpredictable process, and it …