Influence of multiple dose activated charcoal on the disposition kinetics of irinotecan in rats

QY Zhou - Drug metabolism and drug interactions, 2002 - degruyter.com
Introduction: The main clinical adverse effect of irinotecan (CPT-11) therapy is diarrhoea.
Using a rat model, we attempted to study the effects of activated charcoal on the prevention …
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Influence of multiple dose activated charcoal on the disposition kinetics of irinotecan in rats.

C Balram, QY Zhou, YB Cheung… - Drug Metabolism and Drug …, 2002 - europepmc.org
INTRODUCTION: The main clinical adverse effect of irinotecan (CPT-11) therapy is
diarrhoea. Using a rat model, we attempted to study the effects of activated charcoal on the …

Influence of multiple dose activated charcoal on the disposition kinetics of irinotecan in rats

C Balram, QY Zhou, YB Cheung… - Drug metabolism and …, 2002 - pubmed.ncbi.nlm.nih.gov
Introduction The main clinical adverse effect of irinotecan (CPT-11) therapy is diarrhoea.
Using a rat model, we attempted to study the effects of activated charcoal on the prevention …