β2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers

K Niimi, Q Ge, LM Moir, AJ Ammit… - … of Physiology-Lung …, 2012 - journals.physiology.org
β2-Adrenergic receptor (β2AR) agonists induce airway relaxation via cAMP.
Phosphodiesterase (PDE) s degrade and regulate cAMP, and in airway smooth muscle …

beta (2)-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers

K Niimi, Q Ge, L Moir, A Ammit, T Trian… - American Journal Of …, 2012 - opus.lib.uts.edu.au
OPUS at UTS: beta(2)-Agonists upregulate PDE4 mRNA but not protein or activity in human
airway smooth muscle cells from asthmatic and nonasthmatic volunteers - Open Publications …

β2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers

K Niimi, Q Ge, LM Moir, AJ Ammit… - … . Lung cellular and …, 2012 - pubmed.ncbi.nlm.nih.gov
β (2)-Adrenergic receptor (β2AR) agonists induce airway relaxation via cAMP.
Phosphodiesterase (PDE) s degrade and regulate cAMP, and in airway smooth muscle …

[引用][C] β2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers

K NIIMI, QI GE, LM MOIR, AJ AMMIT… - American journal of …, 2012 - pascal-francis.inist.fr
β2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth
muscle cells from asthmatic and nonasthmatic volunteers CNRS Inist Pascal-Francis CNRS …

[PDF][PDF] 2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers

K Niimi, Q Ge, LM Moir, AJ Ammit, T Trian… - Am J Physiol Lung …, 2012 - academia.edu
MATERIALS AND METHODS Culture and treatment. We established primary cultures of
ASM cells derived from human lung tissue (surgical resection, explanted lung or bronchial …

β2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers

K Niimi, Q Ge, LM Moir, AJ Ammit, T Trian… - American Journal of …, 2012 - research.rug.nl
Abstract β (2)-Adrenergic receptor (β2AR) agonists induce airway relaxation via cAMP.
Phosphodiesterase (PDE) s degrade and regulate cAMP, and in airway smooth muscle …

β2-agonists upregulate PDE4 mRNA but not protein, or activity in 3 human airway smooth muscle cells from asthmatic and non 4 asthmatic volunteers 5

K Niimi, Q Ge, LM Moir, AJ Ammit, G Oliver - 2011 - journals.physiology.org
Abstract 39 β2-adrenergic receptor (β2AR) agonists induce airway relaxation via cAMP.
Phosphodiesterase 40 (PDE) s degrade and regulate cAMP, and in airway smooth muscle …

β2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers.

K Niimi, Q Ge, LM Moir, AJ Ammit, T Trian… - American Journal of …, 2011 - europepmc.org
β (2)-Adrenergic receptor (β2AR) agonists induce airway relaxation via cAMP.
Phosphodiesterase (PDE) s degrade and regulate cAMP, and in airway smooth muscle …

[PDF][PDF] 2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers

K Niimi, Q Ge, LM Moir, AJ Ammit, T Trian… - Am J Physiol Lung …, 2012 - scholar.archive.org
MATERIALS AND METHODS Culture and treatment. We established primary cultures of
ASM cells derived from human lung tissue (surgical resection, explanted lung or bronchial …

β 2-agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers

K Niimi, Q Ge, LM Moir, AJ Ammit, T Trian… - American Journal of …, 2012 - opus.lib.uts.edu.au
β 2-agonists are now contraindicated as monotherapy for asthma, and increased PDE4D
has been speculated to contribute to this phenomenon. In this study we investigated the …