Background and aims: Leptin, the product of the ob gene, has been suggested to increase
the risk of colon cancer. However, we have shown that although leptin stimulates epithelial …

Background and aims: Leptin, the product of the ob gene, has been suggested to increase
the risk of colon cancer. However, we have shown that although leptin stimulates epithelial …

Background and aims Leptin, the product of the ob gene, has been suggested to increase
the risk of colon cancer. However, we have shown that although leptin stimulates epithelial …

Leptin stimulates the proliferation of human colon cancer cells in vitro but does not promote
the growth of colon cancer xenografts in nude mice or intestinal tumorigenesis in ApcMin/+mice …

Methods Proliferation of HT-29, LoVo, Caco2, and SW 480 cells was assessed in the
absence or presence of leptin (20-500 ng/ml) by 3H-thymidine incorporation and cell count …

Leptin stimulates the proliferation of human colon cancer cells in vitro but does not promote the
growth of colon cancer xenografts in nude mice or intestinal tumorigenesis in ApcMin/+ mice …

Results: Leptin dose dependently stimulated cell DNA synthesis and growth in all cell lines.
In nude mice, leptin caused a 4.3-fold increase in plasma leptin levels compared with pair …

Background and aims: Leptin, the product of the ob gene, has been suggested to increase
the risk of colon cancer. However, we have shown that although leptin stimulates epithelial …

Results: Leptin dose dependently stimulated cell DNA synthesis and growth in all cell lines.
In nude mice, leptin caused a 4.3-fold increase in plasma leptin levels compared with pair …

The worms may migrate into the ampulla of Vater and enter the bile ducts, gallbladder, or the
pancreatic duct, leading to complications such as biliary colic, gallstone formation …