Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition

MB Ryan, F Fece de la Cruz, S Phat, DT Myers… - Clinical cancer …, 2020 - AACR
Purpose: Although KRAS represents the most commonly mutated oncogene, it has long
been considered an “undruggable” target. Novel covalent inhibitors selective for the …

[HTML][HTML] Vertical pathway inhibition overcomes adaptive feedback resistance to KRASG12C inhibition

MB Ryan, FF de la Cruz, S Phat, DT Myers… - … cancer research: an …, 2020 - ncbi.nlm.nih.gov
Purpose: Although KRAS represents the most commonly mutated oncogene, it has long
been considered an “undruggable” target. Novel covalent inhibitors selective for the KRAS …

[PDF][PDF] Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRAS G12C Inhibition AC

MB Ryan, FF de la Cruz, S Phat, DT Myers, E Wong… - Clin Cancer …, 2020 - academia.edu
Purpose: Although KRAS represents the most commonly mutated oncogene, it has long
been considered an “undruggable” target. Novel covalent inhibitors selective for the …

Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition

MB Ryan, FF de la Cruz, S Phat, DT Myers… - Clinical Cancer …, 2020 - cir.nii.ac.jp
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Although KRAS represents the most commonly mutated oncogene, it has long been …

Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition.

MB Ryan, S Phat, DT Myers, E Wong… - … Cancer Research: an …, 2019 - europepmc.org
Purpose Although KRAS represents the most commonly mutated oncogene, it has long
been considered an" undruggable" target. Novel covalent inhibitors selective for the KRAS …

Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition

MB Ryan, FF de la Cruz, S Phat… - … : an official journal …, 2020 - pubmed.ncbi.nlm.nih.gov
Purpose Although KRAS represents the most commonly mutated oncogene, it has long
been considered an" undruggable" target. Novel covalent inhibitors selective for the KRAS …

Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition.

MB Ryan, S Phat, DT Myers, E Wong… - … Cancer Research: an …, 2019 - europepmc.org
Purpose Although KRAS represents the most commonly mutated oncogene, it has long
been considered an" undruggable" target. Novel covalent inhibitors selective for the KRAS …

Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition

MB Ryan, FF de la Cruz, S Phat… - … : an official journal …, 2020 - pubmed.ncbi.nlm.nih.gov
Purpose Although KRAS represents the most commonly mutated oncogene, it has long
been considered an" undruggable" target. Novel covalent inhibitors selective for the KRAS …