[HTML][HTML] A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

JM Cicchese, A Sambarey, D Kirschner… - Scientific Reports, 2021 - nature.com
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …

A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs.

JM Cicchese, A Sambarey, D Kirschner… - Scientific …, 2021 - search.ebscohost.com
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …

[PDF][PDF] A multi‑scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

JM Cicchese, A Sambarey, D Kirschner3Ε… - Scientific …, 2021 - academia.edu
Results Drug interactions significantly impact in vivo treatment dynamics in GranSim. We
focus on combinations of 2, 3 or 4 drugs involving the first-line antibiotics and two …

A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

J Cicchese, A Sambarey, D Kirschner, J Linderman… - bioRxiv, 2020 - biorxiv.org
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …

[HTML][HTML] A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

JM Cicchese, A Sambarey, D Kirschner… - Scientific …, 2021 - ncbi.nlm.nih.gov
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …

A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

JM Cicchese, A Sambarey, D Kirschner… - Scientific …, 2021 - pubmed.ncbi.nlm.nih.gov
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …

A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

JM Cicchese, A Sambarey, D Kirschner… - Scientific …, 2021 - ui.adsabs.harvard.edu
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …

A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

JM Cicchese, A Sambarey, D Kirschner, JJ Linderman… - Scientific Reports, 2021 - osti.gov
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …

A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs.

JM Cicchese, A Sambarey, D Kirschner… - Scientific …, 2021 - europepmc.org
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …

A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

J Cicchese, A Sambarey, D Kirschner, J Linderman… - 2020 - europepmc.org
Tuberculosis (TB) is the deadliest infectious disease worldwide. The design of new
treatments for TB is hindered by the large number of candidate drugs, drug combinations …