[HTML][HTML] Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - nature.com
Although, a number of pathogenic mutations have been found for Alzheimer's disease (AD),
only one protective mutation has been identified so far in humans. Here we identify possible …

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - ideas.repec.org
Although, a number of pathogenic mutations have been found for Alzheimer's disease (AD),
only one protective mutation has been identified so far in humans. Here we identify possible …

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - econpapers.repec.org
Although, a number of pathogenic mutations have been found for Alzheimer's disease (AD),
only one protective mutation has been identified so far in humans. Here we identify possible …

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - pubmed.ncbi.nlm.nih.gov
Although, a number of pathogenic mutations have been found for Alzheimer's disease (AD),
only one protective mutation has been identified so far in humans. Here we identify possible …

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's diseaselike pathology.

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - search.ebscohost.com
Although, a number of pathogenic mutations have been found for Alzheimer's disease (AD),
only one protective mutation has been identified so far in humans. Here we identify possible …

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology.

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - europepmc.org
Although, a number of pathogenic mutations have been found for Alzheimer's disease (AD),
only one protective mutation has been identified so far in humans. Here we identify possible …

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - cir.nii.ac.jp
抄録< jats: title> Abstract</jats: title>< jats: p> Although, a number of pathogenic mutations
have been found for Alzheimer's disease (AD), only one protective mutation has been …

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - ui.adsabs.harvard.edu
Although, a number of pathogenic mutations have been found for Alzheimer's disease (AD),
only one protective mutation has been identified so far in humans. Here we identify possible …

[HTML][HTML] Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology

K Nagata, M Takahashi, Y Matsuba… - Nature …, 2018 - ncbi.nlm.nih.gov
Although, a number of pathogenic mutations have been found for Alzheimer's disease (AD),
only one protective mutation has been identified so far in humans. Here we identify possible …

[PDF][PDF] Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology

K Nagata, M Takahashi, Y Matsuba… - academia.edu
Results Generation of the App knock-in mice with App 3′-UTR deletion. First, we explored
whether disruption of the endogenous App 3′-UTR prevents Aβ accumulation in our AD …