The Interferon-Alpha Revival in CML

M Talpaz, J Mercer, R Hehlmann - Chronic Myeloid Leukemia, 2021 - Springer
Interferon-alpha (IFNα) was once the standard of frontline treatment for chronic myeloid
leukemia (CML). Its pleiotropic mechanism of action in CML includes immune activation and …

The Interferon-Alpha Revival in CML

M Talpaz, J Mercer, R Hehlmann - Chronic Myeloid Leukemia - Springer
Interferon-alpha (IFNα) demonstrated activity against a variety of solid tumors and myeloid
malignancies in the 1970s and 1980s. The first approved antitumor application for IFNα was …