Case history: Eliquis™(Apixaban), a potent and selective inhibitor of coagulation factor Xa for the prevention and treatment of thrombotic diseases

DJP Pinto, PC Wong, RM Knabb, RR Wexler - Annual Reports in Medicinal …, 2012 - Elsevier
Eliquis™(apixaban) is the culmination of an intense medicinal chemistry effort to identify a
highly optimized inhibitor of coagulation factor Xa (FXa). We sought to identify a safe and …

Case History: EliquisTM (Apixaban), a Potent and Selective Inhibitor of Coagulation Factor Xa for the Prevention and Treatment of Thrombotic Diseases

DJP Pinto, PC Wong, RM Knabb… - Annual Reports in …, 2012 - books.google.com
Despite substantial advances in the prevention and treatment of cardiovascular diseases,
they continue to be the leading cause of death in developed countries and are increasingly …

Case History: EliquisTM (Apixaban), a Potent and Selective Inhibitor of Coagulation Factor Xa for the Prevention and Treatment of Thrombotic Diseases

DJP Pinto, PC Wong, RM Knabb… - Annual Reports in …, 2012 - books.google.com
Despite substantial advances in the prevention and treatment of cardiovascular diseases,
they continue to be the leading cause of death in developed countries and are increasingly …