[PDF][PDF] Anti‐influenza drug discovery: identification of an orally bioavailable quinoline derivative through activity‐and property‐guided lead optimization

MS Coumar, S Ko - researchgate.net
All commercial chemicals and solvents are reagent grade and were used without further
treatment unless otherwise noted. All reactions were carried out under an atmosphere of dry …

Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity-and property-guided lead optimization

JY Yeh, MS Coumar, HY Shiao, TJ Lin, YC Lee… - 2012 - ir.nhri.org.tw
From a high-throughput screening (HTS) hit with inhibitory activity against virus-induced
cytophathic in the low micromolar range, we have developed a potent anti-influenza lead …

[引用][C] Anti‐influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative through Activity‐and Property‐Guided Lead Optimization

JY Yeh, MS Coumar, HY Shiao, TJ Lin, YC Lee… - …, 2012 - Wiley Online Library
The necessity to develop additional defenses against influenza virus was felt acutely during
the 2009 H1N1 swine-origin influenza virus (S-OIV) pandemic. In response to the outbreak …

Anti-influenza drug discovery: identification of an orally bioavailable quinoline derivative through activity-and property-guided lead optimization

JY Yeh, MS Coumar, HY Shiao, TJ Lin… - …, 2012 - pubmed.ncbi.nlm.nih.gov
From a high-throughput screening (HTS) hit with inhibitory activity against virus-induced
cytophathic in the low micromolar range, we have developed a potent anti-influenza lead …

[引用][C] Anti-influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative through Activity-and Property-Guided Lead Optimization

JY Yeh, MS Coumar, HY Shiao, TJ Lin… - …, 2012 - researchoutput.ncku.edu.tw
Anti-influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative
through Activity- and Property-Guided Lead Optimization — National Cheng Kung University …

Anti-influenza drug discovery: identification of an orally bioavailable quinoline derivative through activity-and property-guided lead optimization.

JY Yeh, MS Coumar, HY Shiao, TJ Lin, YC Lee… - …, 2012 - europepmc.org
From a high-throughput screening (HTS) hit with inhibitory activity against virus-induced
cytophathic in the low micromolar range, we have developed a potent anti-influenza lead …

Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity-and property-guided lead optimization

JY Yeh, MS Coumar, HY Shiao, TJ Lin, YC Lee… - 2012 - 211.76.174.198
From a high-throughput screening (HTS) hit with inhibitory activity against virus-induced
cytophathic in the low micromolar range, we have developed a potent anti-influenza lead …

[引用][C] Anti-influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative through Activity-and Property-Guided Lead Optimization

JY Yeh, MS Coumar, HY Shiao, TJ Lin, YC Lee… - …, 2012 - pure.lib.cgu.edu.tw
Anti-influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative
through Activity- and Property-Guided Lead Optimization — 長庚大學 跳至主導覽 跳至搜尋 跳過 …

[引用][C] Anti-influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative through Activity-and Property-Guided Lead Optimization

JY Yeh, MS Coumar, HY Shiao, TJ Lin, YC Lee… - …, 2012 - pure.lib.cgu.edu.tw
Anti-influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative
through Activity- and Property-Guided Lead Optimization — Chang Gung University Skip to main …

Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity-and property-guided lead optimization

JY Yeh, MS Coumar, HY Shiao, TJ Lin, YC Lee… - 2012 - ir.nhri.org.tw
From a high-throughput screening (HTS) hit with inhibitory activity against virus-induced
cytophathic in the low micromolar range, we have developed a potent anti-influenza lead …