Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

IM Serafimova, MA Pufall, S Krishnan, K Duda… - Nature chemical …, 2012 - nature.com
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …
被引用次数：579 相关文章

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles.

IM Serafimova, MA Pufall, S Krishnan… - Nature Chemical …, 2012 - search.ebscohost.com
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

IM Serafimova, MA Pufall, S Krishnan… - Nature Chemical …, 2012 - ohsu.elsevierpure.com
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …
[PDF] academia.edu

[PDF][PDF] Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

IM Serafimova, MA Pufall, S Krishnan, K Duda… - Nat Chem Biol - academia.edu
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …
[PDF] ucsf.edu

[PDF][PDF] Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

IM Serafimova, MA Pufall, S Krishnan, K Duda… - tauntonlab.ucsf.edu
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles.

IM Serafimova, MA Pufall, S Krishnan… - Nature Chemical …, 2012 - europepmc.org
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

IM Serafimova - 2013 - search.proquest.com
Targeting non-catalytic cysteine residues with irreversible electrophiles improved the
selectivity and potency of various inhibitors. This strategy has been applied to scaffolds …

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

IM Serafimova, MA Pufall, S Krishnan… - Nature chemical …, 2012 - pubmed.ncbi.nlm.nih.gov
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

IM Serafimova, MA Pufall, S Krishnan, K Duda… - Nature chemical …, 2012 - iro.uiowa.edu
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …
[PDF] researchgate.net

[PDF][PDF] Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

IM Serafimova, MA Pufall, S Krishnan, K Duda… - Nat Chem Biol - researchgate.net
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a
powerful approach for enhancing pharmacological potency and selectivity. Nevertheless …