Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers

G Hatzivassiliou, JR Haling, H Chen, K Song, S Price… - Nature, 2013 - nature.com
KRAS and BRAF activating mutations drive tumorigenesis through constitutive activation of
the MAPK pathway. As these tumours represent an area of high unmet medical need …

Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers.

G Hatzivassiliou, JR Haling, H Chen, K Song, S Price… - Nature, 2013 - europepmc.org
KRAS and BRAF activating mutations drive tumorigenesis through constitutive activation of
the MAPK pathway. As these tumours represent an area of high unmet medical need …

Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers

G Hatzivassiliou, JR Haling, H Chen, K Song… - …, 2013 - ui.adsabs.harvard.edu
KRAS and BRAF activating mutations drive tumorigenesis through constitutive activation of
the MAPK pathway. As these tumours represent an area of high unmet medical need …

Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers.

G Hatzivassiliou, JR Haling, H Chen, K Song… - …, 2013 - search.ebscohost.com
KRAS and BRAF activating mutations drive tumorigenesis through constitutive activation of
the MAPK pathway. As these tumours represent an area of high unmet medical need …

Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers

G Hatzivassiliou, JR Haling, H Chen, K Song, S Price… - Nature, 2013 - go.gale.com
KRAS and BRAF activating mutations drive tumorigenesis through constitutive activation of
the MAPK pathway. As these tumours represent an area of high unmet medical need …

[引用][C] Erratum: Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers

G Hatzivassiliou, JR Haling, H Chen, K Song, S Price… - Nature, 2013 - nature.com
In this Letter, the statement:'The authors declare competing financial interests: details
accompany the full-text HTML version of the paper at www. nature. com/nature.'was missing …

Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers

G Hatzivassiliou, JR Haling, H Chen, K Song, S Price… - Nature, 2013 - ideas.repec.org
The mechanism of action of three different allosteric MEK inhibitors that target the MAP
kinase pathway is investigated, and their efficacy is shown to be explained by the distinct …

[引用][C] Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers

G Hatzivassiliou, JR Haling, H Chen, K Song, S Price… - Nature, 2013 - cir.nii.ac.jp
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven
cancers | CiNii Research CiNii 国立情報学研究所 学術情報ナビゲータ[サイニィ] 詳細へ移動 検索 …

Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers

G Hatzivassiliou, JR Haling, H Chen, K Song… - Nature, 2013 - econpapers.repec.org
The mechanism of action of three different allosteric MEK inhibitors that target the MAP
kinase pathway is investigated, and their efficacy is shown to be explained by the distinct …

Mechanism of MEK inhibition determines efficacy in mutant KRAS-versus BRAF-driven cancers

G Hatzivassiliou, JR Haling, H Chen, K Song, S Price… - Nature, 2013 - oak.novartis.com
KRAS and BRAF activating mutations drive tumorigenesis through constitutive activation of
the MAPK pathway. As these tumours represent an area of high unmet medical need …