Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - Elife, 2020 - elifesciences.org
Molecular-glue degraders mediate interactions between target proteins and components of
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
[HTML][HTML] Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - eLife, 2020 - ncbi.nlm.nih.gov
Molecular-glue degraders mediate interactions between target proteins and components of
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation.
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - Elife, 2020 - europepmc.org
Molecular-glue degraders mediate interactions between target proteins and components of
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger Cyclin K degradation
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - bioRxiv, 2020 - biorxiv.org
Molecular glues are small molecules that exert their biologic or therapeutic activities by
inducing gain-of-function interactions between pairs of proteins. In particular, molecular-glue …
inducing gain-of-function interactions between pairs of proteins. In particular, molecular-glue …
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - 2020 - agris.fao.org
Molecular-glue degraders mediate interactions between target proteins and components of
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - …, 2020 - pubmed.ncbi.nlm.nih.gov
Molecular-glue degraders mediate interactions between target proteins and components of
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - eLife, 2020 - cir.nii.ac.jp
抄録< jats: p> Molecular-glue degraders mediate interactions between target proteins and
components of the ubiquitin-proteasome system to cause selective protein degradation …
components of the ubiquitin-proteasome system to cause selective protein degradation …
[PDF][PDF] Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger Cyclin K degradation
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - scholar.archive.org
Molecular glues are small molecules that exert their biologic or therapeutic activities by
inducing gain-of-function interactions between pairs of proteins. In particular, molecular-glue …
inducing gain-of-function interactions between pairs of proteins. In particular, molecular-glue …
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation.
L Lv, P Chen, L Cao, Y Li, Z Zeng, Y Cui, Q Wu, J Li… - Elife, 2020 - europepmc.org
Molecular-glue degraders mediate interactions between target proteins and components of
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …
the ubiquitin-proteasome system to cause selective protein degradation. Here, we report a …