Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair

JE Peabody Lever, Q Li, N Pavelkova, SS Hussain… - bioRxiv, 2024 - biorxiv.org
Rationale: The role of MUC5B mucin expression in IPF pathogenesis is unknown.
Bleomycin-exposed rodent models do not exhibit sustained fibrosis or airway remodeling …
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Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair

JEP Lever, Q Li, N Pavelkova, SS Hussain, S Bakshi… - bioRxiv - ncbi.nlm.nih.gov
Methods Bleomycin (5U/kg) or saline-control was micro-sprayed intratracheally then wild-
type ferrets were evaluated through 22 wks. Clinical phenotype was assessed with lung …

Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair

JEP Lever, Q Li, N Pavelkova… - … : the preprint server …, 2024 - pubmed.ncbi.nlm.nih.gov
Rationale The role of MUC5B mucin expression in IPF pathogenesis is unknown. Bleomycin-
exposed rodent models do not exhibit sustained fibrosis or airway remodeling. Unlike mice …
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[HTML][HTML] Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair

JEP Lever, Q Li, N Pavelkova, SS Hussain, S Bakshi… - bioRxiv, 2024 - biorxiv.org
Rationale: The role of MUC5B mucin expression in IPF pathogenesis is unknown.
Bleomycin-exposed rodent models do not exhibit sustained fibrosis or airway remodeling …

Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair

PL JE, Q Li, N Pavelkova, SS Hussain, S Bakshi… - 2024 - europepmc.org
Methods: Bleomycin (5U/kg) or saline-control was micro-sprayed intratracheally then wild-
type ferrets were evaluated through 22 wks. Clinical phenotype was assessed with lung …