Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors
AA El-Malah, MM Gineinah, MT Khayat… - Frontiers in …, 2024 - frontiersin.org
Introduction: Phosphodiesterase 7 (PDE7) is a high-affinity cyclic AMP (cAMP)-specific PDE
that is expressed in immune and proinflammatory cells. In this work, we explore the …
that is expressed in immune and proinflammatory cells. In this work, we explore the …
Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors
AA El-Malah, MM Gineinah… - Frontiers in …, 2024 - pubmed.ncbi.nlm.nih.gov
Introduction: Phosphodiesterase 7 (PDE7) is a high-affinity cyclic AMP (cAMP)-specific PDE
that is expressed in immune and proinflammatory cells. In this work, we explore the …
that is expressed in immune and proinflammatory cells. In this work, we explore the …
Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors
MM Safar - 2024 - buescholar.bue.edu.eg
Abstract Introduction: Phosphodiesterase 7 (PDE7) is a high-affinity cyclic AMP (cAMP)-
specific PDE that is expressed in immune and proinflammatory cells. In this work, we explore …
specific PDE that is expressed in immune and proinflammatory cells. In this work, we explore …
[PDF][PDF] Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors
AA El-Malah, MM Gineinah, MT Khayat, AS Aljahdali… - 2024 - researchgate.net
Methods: A series of novel substituted 4-hydrazinoquinazoline derivatives and fused
triazoloquinazolines were designed, synthesized, and evaluated in vitro for their PDE7A …
triazoloquinazolines were designed, synthesized, and evaluated in vitro for their PDE7A …
Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors.
AA El-Malah, MM Gineinah, MT Khayat… - Frontiers in …, 2024 - europepmc.org
Abstract Introduction: Phosphodiesterase 7 (PDE7) is a high-affinity cyclic AMP (cAMP)-
specific PDE that is expressed in immune and proinflammatory cells. In this work, we explore …
specific PDE that is expressed in immune and proinflammatory cells. In this work, we explore …
[HTML][HTML] Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors
AA El-Malah, MM Gineinah, MT Khayat… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Abstract Introduction: Phosphodiesterase 7 (PDE7) is a high-affinity cyclic AMP (cAMP)-
specific PDE that is expressed in immune and proinflammatory cells. In this work, we explore …
specific PDE that is expressed in immune and proinflammatory cells. In this work, we explore …
[PDF][PDF] Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors
AA El-Malah, MM Gineinah, MT Khayat, AS Aljahdali… - 2024 - researchgate.net
Methods: A series of novel substituted 4-hydrazinoquinazoline derivatives and fused
triazoloquinazolines were designed, synthesized, and evaluated in vitro for their PDE7A …
triazoloquinazolines were designed, synthesized, and evaluated in vitro for their PDE7A …