Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT)

H Deng, H O'Keefe, CP Davie, KE Lind… - Journal of medicinal …, 2012 - ACS Publications
The metalloprotease ADAMTS-5 is considered a potential target for the treatment of
osteoarthritis. To identify selective inhibitors of ADAMTS-5, we employed encoded library …

Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT)

H Deng, H O'Keefe, CP Davie… - Journal of …, 2012 - pubmed.ncbi.nlm.nih.gov
The metalloprotease ADAMTS-5 is considered a potential target for the treatment of
osteoarthritis. To identify selective inhibitors of ADAMTS-5, we employed encoded library …

Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).

H Deng, H O'Keefe, CP Davie, KE Lind… - Journal of Medicinal …, 2012 - europepmc.org
The metalloprotease ADAMTS-5 is considered a potential target for the treatment of
osteoarthritis. To identify selective inhibitors of ADAMTS-5, we employed encoded library …

[引用][C] Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT …

H Deng, H O'Keefe, CP Davie, KE Lind… - Journal of Medicinal …, 2012 - cir.nii.ac.jp
Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit
Human Cartilage Degradation via Encoded Library Technology (ELT) | CiNii Research CiNii …