[HTML][HTML] Multitarget effects of Korean red ginseng in animal model of Parkinson's disease: antiapoptosis, antioxidant, antiinflammation, and maintenance of blood …

JH Choi, M Jang, SY Nah, S Oh, IH Cho - Journal of ginseng research, 2018 - Elsevier
… to the protection of dopaminergic neurons from MPTP-… antioxidant activity which protects
neurons from the oxidative … a critical role in protecting against various inflammatory disorders [40]…

[HTML][HTML] Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model

TSZ Fang, Y Sun, AC Pearce, S Eleuteri… - Nature …, 2023 - nature.com
… in Usp30 knockout mice protects against behavioral deficits and leads to increased
mitophagy, decreased phospho-S129 αSyn, and attenuation of SN dopaminergic neuronal loss …

Treating Parkinson's disease by astrocyte reprogramming: Progress and challenges

ZYD Wei, AK Shetty - Science Advances, 2021 - science.org
… midbrain astrocytes into functional DA-ergic neurons in a mouse model of PD is an exciting
… the lost DA-ergic neurons in PD. Since this study was performed in a mouse model of PD, it …

Toxin models of mitochondrial dysfunction in Parkinson's disease

TN Martinez, JT Greenamyre - Antioxidants & redox signaling, 2012 - liebertpub.com
… null mutations for DAT were completely protected from MPTP-induced cell death (36). …
neurons and associated changes in colon motility in an MPTP mouse model of Parkinson's disease

Macrophage delivery of therapeutic nanozymes in a murine model of Parkinson's disease

AM Brynskikh, Y Zhao, RL Mosley, S Li, MD Boska… - …, 2010 - Future Medicine
… nanozyme in the Parkinson’s disease mouse model: pathway I: BMM … in significant protection
of nigrostratial neurons against MPTP-… in the MPTP model of Parkinson disease. Nat. Med.5…

Nicotine improved the olfactory impairment in MPTP-induced mouse model of Parkinson's disease

J Yang, DJ Lv, LX Li, YL Wang, D Qi, J Chen, CJ Mao… - Neurotoxicology, 2019 - Elsevier
… Our results suggested that nicotine could improve the olfactory impairment by protecting
cholinergic systems in the OB of MPTP-treated mice. And nicotine protection of cholinergic …

… α-synuclein levels by promoting mitochondrial function and autophagy possibly via SIRT1 in the chronic MPTP/P-induced mouse model of Parkinson's disease

JH Koo, JY Cho - Neurotoxicity research, 2017 - Springer
… In conclusion, our results indicate that TE protects against DAergic neuron loss and α-Syn-mediated
toxicity and may rescue chronic MPTP/P-induced motor deficits by reducing α-Syn …

[HTML][HTML] Effects of mesenchymal stem cell on dopaminergic neurons, motor and memory functions in animal models of Parkinson's disease: a systematic review and …

JM Park, M Rahmati, SC Lee, JI Shin… - Neural Regeneration …, 2024 - journals.lww.com
… Mesenchymal stem cells have been shown to positively impact motor function and memory
function and protect dopaminergic neurons in preclinical models of Parkinson's disease. …

[HTML][HTML] The neuroprotection of low-dose morphine in cellular and animal models of Parkinson's disease through ameliorating endoplasmic reticulum (ER) stress and …

B Wang, CJ Su, TT Liu, Y Zhou, Y Feng… - Frontiers in molecular …, 2018 - frontiersin.org
… Morphine protected neurons against neurotoxicity induced by Aβ oligomers, which is
involved in the pathogenesis of Alzheimer’s disease (Wang Y. et al., 2015). Thus, these results …

Animal models of Parkinson's disease progression

GE Meredith, PK Sonsalla, MF Chesselet - Acta neuropathologica, 2008 - Springer
… before 6-OHDA protects NE neurons [11]. The degree of loss of DA neurons and their striatal
… Overall, the MPTP-treated mouse models are disappointing in that DA neurons die so …