[HTML][HTML] Bushen-Yizhi formula alleviates neuroinflammation via inhibiting NLRP3 inflammasome activation in a mouse model of Parkinson's disease

Y Mo, E Xu, R Wei, B Le, L Song, D Li… - … Complementary and …, 2018 - hindawi.com
… reveal that BSYZ protects against the motor deficits, dopaminergic neuronal degeneration, …
Marconi, “Factors associated with motor fluctuations and dyskinesia in Parkinson disease: …

… Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease

NA Kaidery, R Banerjee, L Yang… - Antioxidants & redox …, 2013 - liebertpub.com
mice also showed increased vulnerability to the loss of TH-positive neurons as compared to
MPTP-treated WT mice… positive neurons in the SNpc in WT mice, but failed to protect against …

Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease

GE Meredith, S Totterdell, M Beales, CK Meshul - Experimental neurology, 2009 - Elsevier
… A formidable challenge in the field of Parkinson's disease (PD) research is to understand
the processes that lead to the death of dopamine (DA)-containing neurons in the substantia …

Behavioral tests in neurotoxin-induced animal models of Parkinson's disease

EM Prasad, SY Hung - Antioxidants, 2020 - mdpi.com
neuronal apoptosis. Since no current treatment can cure PD, using a suitable PD animal
model … different neurotoxin-induced PD animal models with their mechanisms of pathogenesis …

Microglial activation damages dopaminergic neurons through MMP-2/-9-mediated increase of blood-brain barrier permeability in a Parkinson's disease mouse model

Z Ruan, D Zhang, R Huang, W Sun, L Hou… - International journal of …, 2022 - mdpi.com
… of water channel protein aquaporin 4 expressed in astrocyte, a cell component of neurovascular
unit, to BBB reduces brain edema and accelerates functional recovery in rodent models

Calcium, ageing, and neuronal vulnerability in Parkinson's disease

DJ Surmeier - The Lancet Neurology, 2007 - thelancet.com
Parkinson's disease. For example, there is considerable regional variability in the vulnerability
of dopamine neurons in Parkinson's disease, … Rejuvenated SNc dopamine neurons spike …

Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease

MS Shchepinov, VP Chou, E Pollock, JW Langston… - Toxicology letters, 2011 - Elsevier
… Taken together, these findings indicate that dietary isotopic reinforcement with D-PUFA
partially protects against nigrostriatal damage from oxidative injury elicited by MPTP in mice. …

MPTP neurotoxicity: actions, mechanisms, and animal modeling of Parkinson's disease

M Ferrucci, F Fornai - Handbook of Neurotoxicity, 2021 - Springer
… In fact, the selective neurotoxicity induced by MPTP rejuvenated … Association of Parkinson
disease induction with cardiac … miR-7 and miR-153 protect neurons against MPP(+)-induced …

Protective effects of intranasal losartan in the APP/PS1 transgenic mouse model of Alzheimer disease

L Danielyan, R Klein, LR Hanson, M Buadze… - Rejuvenation …, 2010 - liebertpub.com
… law for the protection of animals. All experiments were approved by the local … model of
parkinson's disease is mediated by brain angiotensin: Relevance to progression of the diseaseJ …

Channel switch rejuvenates neurons

B Hughes - Nature Reviews Drug Discovery, 2007 - nature.com
… ) region degenerate and die in Parkinson's disease (PD) is not … an animal model of PD —
and thereby inducing adult neuronsneurons for pacemaking — the neurons can be protected