[HTML][HTML] Flavonoids as therapeutic agents in Alzheimer's and Parkinson's diseases: a systematic review of preclinical evidences
RB de Andrade Teles, TC Diniz, TCC Pinto… - … medicine and cellular …, 2018 - ncbi.nlm.nih.gov
… in animal models for Alzheimer's and Parkinson's diseases. … signaling pathways, protect
neurons against oxidative stress, … The result showed that treatment leads to a significant revival …
neurons against oxidative stress, … The result showed that treatment leads to a significant revival …
Tinospora cordifolia Suppresses Neuroinflammation in Parkinsonian Mouse Model
… protects dopaminergic neurons by suppressing neuroinflammation in MPTP-induced
Parkinsonian mouse model… neurodegeneration in a rat model of Parkinson disease. Proceedings …
Parkinsonian mouse model… neurodegeneration in a rat model of Parkinson disease. Proceedings …
GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model
P Hadaczek, G Wu, N Sharma, A Ciesielska… - Experimental …, 2015 - Elsevier
… These findings suggest that a truly disease-modifying strategy for PD would … neurons
throughout the central and peripheral nervous systems. A direct route to that would be the revival of …
throughout the central and peripheral nervous systems. A direct route to that would be the revival of …
Disease-modifying drugs in Parkinson's disease
A Park, M Stacy - Drugs, 2015 - Springer
… cell death, prevention of nigral dopaminergic neuron death in … ) mouse model, protection
of hippocampal neurons in the rat kainic acid model, and neurorescue of hippocampal neurons …
of hippocampal neurons in the rat kainic acid model, and neurorescue of hippocampal neurons …
Small molecule TrkB agonist deoxygedunin protects nigrostriatal dopaminergic neurons from 6-OHDA and MPTP induced neurotoxicity in rodents
… -tetrahydropyridine (MPTP)-induced mice model of Parkinson's disease. Rats were treated
with … animal models such as rotenone models for Parkinson's disease deserves further study. …
with … animal models such as rotenone models for Parkinson's disease deserves further study. …
[HTML][HTML] SRT1720 as an SIRT1 activator for alleviating paraquat-induced models of Parkinson's disease
CC Chao, CL Huang, JJ Cheng, CT Chiou, IJ Lee… - Redox Biology, 2022 - Elsevier
… animal models of PD. Here we show that SRT1720 alleviates PQ-induced toxicity in cell and
animal models… To validate the protection of SRT1720 against PQ-induced cytotoxicity within …
animal models… To validate the protection of SRT1720 against PQ-induced cytotoxicity within …
[HTML][HTML] The role of reactive oxygen species in the pathogenesis of Alzheimer's disease, Parkinson's disease, and Huntington's disease: a mini review
S Manoharan, GJ Guillemin… - … medicine and cellular …, 2016 - hindawi.com
… neurodegenerative diseases using suitable animal models. This … neuronal cells and concluded
that the antioxidant property of rutin might have played a role in the protection of neuronal …
that the antioxidant property of rutin might have played a role in the protection of neuronal …
… delivery of bone marrow-derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer's and Parkinson's disease
… /PS1 model) or α-synuclein [MSCs in (Thy1)-h[A30P] aS model… of transgenic PD and AD
mouse models. Additional work is … improvement in these mouse models with intranasal microglia/…
mouse models. Additional work is … improvement in these mouse models with intranasal microglia/…
The effect of docosahexaenoic acid on apelin distribution of nervous system in the experimental mouse model of Parkinson's disease
… Parkinson's disease (PD) is a progressive and the most common neurodegenerative disorder
after Alzheimer's disease (… Regarding our findings, supplementary DHA protects brain and …
after Alzheimer's disease (… Regarding our findings, supplementary DHA protects brain and …
Neuroprotective and neuro-restorative effects of minocycline and rasagiline in a zebrafish 6-hydroxydopamine model of Parkinson's disease
A Cronin, M Grealy - Neuroscience, 2017 - Elsevier
… , which is widely used to produce animal models of idiopathic Parkinson’s disease. It causes
… Our findings that rasagiline both protects and restores neurons from the effects of 6-OHDA, …
… Our findings that rasagiline both protects and restores neurons from the effects of 6-OHDA, …