[HTML][HTML] … -induced responses, anxiety, hypercortisolemia, and organometry of early peripheral immunoendocrine impairment in adult 3xTg-AD mice and their long …

R Baeta-Corral, M De la Fuente… - Behavioural Brain …, 2023 - Elsevier
… and female 3xTg-AD mice exhibit worse nesting behavior than … normal levels, an activated
central HPA axis with altered … receptor, and ACTH in several stress- and emotionality-related …

Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer's disease-associated markers in 3xTg-AD mice

M Kapadia, MF Mian, D Ma, CP Hutton, A Azam… - Alzheimer's Research & …, 2021 - Springer
… early manifestations of systemic autoimmunity, increased … to 3xTg-AD males, 1-year-old
3xTg-AD females still show … in the context of the altered 3xTg-AD phenotype, the current study …

[HTML][HTML] … in the basolateral amygdala and cholinergic fiber loss in the cortex but not cognitive behavioral symptoms in a triple transgenic mouse model of alzheimer's …

S Farkas, A Szabó, B Török, C Sólyomvári… - Frontiers in …, 2022 - frontiersin.org
… 4-month-old 3xTg-AD mice only after hormone depletion. Three-… (IV) At the structural level,
we were concentrating on … Cognitive z-score was calculated from alteration in the Y-maze; …

Chronic fragmentation of the daily sleep-wake rhythm increases amyloid-beta levels and neuroinflammation in the 3xTg-AD mouse model of Alzheimer's disease

MJ Duncan, LE Guerriero, K Kohler, LE Beechem… - Neuroscience, 2022 - Elsevier
… revealed that sleep fragmentation altered the daily sleep-wake … Our findings of increased
following sleep fragmentation … Sex-dependent alterations in social behaviour and cortical …

Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical and pTau in a mouse model of Alzheimer's disease

SM Rothman, N Herdener, KA Frankola, MR Mughal… - Brain research, 2013 - Elsevier
… of oligomers and pTau were not significantly changed in … to cause a sustained level of
stress in 3xTgAD mice. In studies … to acclimate to social stress, 3xTgAD mice also display an …

Age and gender differences for the behavioral phenotypes of 3xTg Alzheimer's disease mice

T Pairojana, S Phasuk, P Suresh, SP Huang… - Brain Research, 2021 - Elsevier
… Male 3xTg-AD mice exhibit normal sensory and locomotor … behavioral phenotypes for the
two genders of 3xTg-AD mice at … In 3xTg-AD mice, plaques occur at around three months old…

Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice

A Van der Jeugd, A Parra-Damas, R Baeta-Corral… - Scientific Reports, 2018 - nature.com
increased after Se treatment in 3xTg-AD mice (69%). … that coincides with memory deficits
4 , we next quantified -… walling, grooming and chewing are not altered. Interestingly, Se …

Chronic anatabine treatment reduces Alzheimer's disease (AD)-like pathology and improves socio-behavioral deficits in a transgenic mouse model of AD

M Verma, D Beaulieu-Abdelahad, G Ait-Ghezala, R Li… - PLoS …, 2015 - journals.plos.org
… In the elevated plus maze, Tg PS1/APPswe mice exhibited … This does not alter the authors'
adherence to PLOS ONE … of , neuroinflammation and behavior in a transgenic mouse

PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and

D Arsenault, A Dal-Pan, C Tremblay… - Journal of …, 2013 - Soc Neuroscience
behavior of rodents in response to the mild stressors novel … no alteration of soluble
phospho-PAK in 3xTg-AD mice at 4, 12… of a higher anxiety level in 3xTg-AD mice, which, however, …

Reduced social investigation and increased injurious behavior in transgenic 5xFAD mice

F Kosel, JS Hamilton, SL Harrison… - Journal of …, 2021 - Wiley Online Library
… In contrast, the 3xTg-AD strain exhibits neurofibrillary tangles … at 9 months of age, relative
to transgenic 5xFAD mice on … aggressor and target mouse exhibit altered behaviors, thereby …