Citalopram restores short-term memory deficit and non-cognitive behaviors in APP/PS1 mice while halting the advance of Alzheimer's disease-like pathology

Q Zhang, C Yang, T Liu, L Liu, F Li, Y Cai, K Lv, X Li… - …, 2018 - Elsevier
… In terms of previous research, SSRIs could increase … found to reduce in the brain interstitial
fluid in a mouse model of … noticed that chronic administration of citalopram did not alter the …

Repeated multi-domain cognitive training prevents cognitive decline, anxiety and amyloid pathology found in a mouse model of Alzheimer disease

J Mehla, SH Deibel, H Karem, NS Hong… - Communications …, 2023 - nature.com
… and reduces tau and pathology in 3xTg-AD animals 14 . … In summary, APP NL-GF/NL-GF
mice showed elevated … The platform position was changed at each time point to rule out …

Burying and Burrowing Behavior in Male and Female Normal and 3xTg-AD Mice: A New Comprehensive Study Based on the Two-Zone Configuration.

M Santana-Santana, JR Bayascas, L Giménez-Llort - 2022 - preprints.org
… function, testing pain and stress, and modeling neurological … the digging behavior is
performed since they can alter the … the 3xTg-AD males show an increase in burrowing behavior

High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner

OJ Gannon, LS Robison, AE Salinero… - Journal of …, 2022 - Springer
… were tested for exploratory activity and anxiety-like behavior in … effects of chronic cerebral
hypoperfusion in 3xTg-AD mice [51], … in levels in 3xTg-AD mice [51]; however, this was after

[HTML][HTML] IL-34 exacerbates pathogenic features of Alzheimer's disease and calvaria osteolysis in triple transgenic (3x-Tg) female mice

A Ho, B Ngala, C Yamada, C Garcia, C Duarte… - Biomedicine & …, 2023 - Elsevier
… with their social interaction behavior display elevated serum … 3x-Tg mice using the Y-maze
spontaneous alteration test [51]… demonstrated that elevated production of peptides from …

Amyloid beta-related alterations to glutamate signaling dynamics during Alzheimer's disease progression

CA Findley, A Bartke, KN Hascup, ER Hascup - ASN neuro, 2019 - journals.sagepub.com
… explore the -related changes to the tripartite glutamate synapse resulting in altered cell …
In 3xTg-AD mice, GS+ astrocyte distribution mirrored that of GFAP+ distribution in the DG and …

Both amyloid-β peptide and tau protein are affected by an anti-amyloid-β antibody fragment in elderly 3xTg-AD mice

AR Roda, L Montoliu-Gaya, G Serra-Mir… - International journal of …, 2020 - mdpi.com
oligomers [21] and intracellular levels [22] after a single … not altered with respect to
those in the untreated 3xTg-AD. … levels increased in 5-month-old 3xTg-AD female mice [21], the …

Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice

ASR Sierksma, J Prickaerts, L Chouliaras… - Neurobiology of …, 2013 - Elsevier
… in blood plasma before and after an acute stressor to explore HPA axis … that both sexes exhibit
an altered behavioral phenotype in … in AD mouse models demonstrated an increase in

Neuroprotective effects of ceftriaxone involve the reduction of burden and neuroinflammatory response in a mouse model of Alzheimer's disease

MA Tikhonova, TG Amstislavskaya, YJ Ho… - Frontiers in …, 2021 - frontiersin.org
… effects of CEF on behavior, deposition, and associated … Aversive bright lighting (1,000
lx) and the stress of being in the … increased in mice of the Aβ25–35 + saline group to the level

Loss of SST and PV positive interneurons in the ventral hippocampus results in anxiety-like behavior in 5xFAD mice

H Li, J Zhao, L Lai, Y Xia, C Wan, S Wei, J Liang… - Neurobiology of …, 2022 - Elsevier
… anxiety-like behavior and increased E/I balance in 5xFAD mice, we … While we found no
altered in the sEPSCs and sIPSCs … For example, mice exposed to chronic stress exhibited E/I …