… elevated plus maze, and the dark/light box [20–23]. Interestingly, in 6-month-old 3xTg-AD
mice, the intraneuronal Aβ … signaling are altered in seven-month-old male 3xTg-AD mice, when …

… engaged in active copying-with-stress strategies [22]. Here, … Therefore, when the previous
actions are altered, as it is the … anxious-like profile exhibited since young adulthood [8]. Several …

… observed a significant increase in brain Aβ 1–42 , Aβ 1–40 … Aβ and p-tau content in 11-month-old
3xTg-AD female mice (in … properties) and by altering mitochondrial dynamics, ultimately …

… -β (Aβ) and tau pathologies might alter the monoamine release … 3×Tg-AD mice in two models
of stress-coping behavior (FST … the hypothesis of increased depression-like behavior and …

… On the other hand, AD-related presenilin mutations can alter … APP/PS1, 3xTg-AD, and
5xFAD mouse models of AD have … that can rapidly manifest both the Aβ plaques and NFTs is …

… and female 3xTg-AD mice regarding behavioral impairment (… , the higher level of insulin in
the plasma of non-Tg mice may … , 52), suggesting altered insulin clearance in 3xTg-AD mice. …

… App NL mice at different time points, using the elevated plus maze, … None of these App-KI
mice exhibit tau pathology or severe … test experience could alter anxiety-related behavior, we re-…

… pm) and after metabolic and behavior experiments to avoid potential stress induction by the
… HFD exposure significantly increased the levels of soluble Aβ 40 in 3xTg-AD mice (p = 0.02). …

… increased the levels of NEP and IDE and decreased Aβ levels… in treated Tg mice is not due
to altered locomotor behavior. … be observed at later time points in 3xTg-AD mice and were not …

… of behavioral function, reduction of Aβ*56 oligomer levels and immunomodulation in the …
chronic diseases [33], and is increased in the CSF of AD patients [56]. We also report altered pro…