[HTML][HTML] Ethanol exposure alters Alzheimer's-related pathology, behavior, and metabolism in APP/PS1 mice

SM Day, SC Gironda, CW Clarke, JA Snipes… - Neurobiology of …, 2023 - Elsevier
… that ethanol may increase deposition by disrupting … APP/PS1 mice exhibited increased
locomotor activity and central … to identify whether ethanol could alter glucose tolerance. Instead…

Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice

ASR Sierksma, J Prickaerts, L Chouliaras… - Neurobiology of …, 2013 - Elsevier
… in blood plasma before and after an acute stressor to explore HPA axis … that both sexes exhibit
an altered behavioral phenotype in … in AD mouse models demonstrated an increase in

Melatonin induces mechanisms of brain resilience against neurodegeneration

R Corpas, C Griñán‐Ferré… - Journal of Pineal …, 2018 - Wiley Online Library
… treatment improved metabolism in 3xTg-AD mice by … in senile plaques formation were
changed by the treatment. The … of APP processing in 3xTg-AD mice after the chronic treatment. …

[HTML][HTML] Ryanodine receptors: physiological function and deregulation in Alzheimer disease

D Del Prete, F Checler, M Chami - Molecular neurodegeneration, 2014 - Springer
… , we recently reported a global alteration of Ca 2+ homeostasis … from the triple transgenic
mice model 3xTg-AD (knock in for the … the increase observed in PS2 transgenic mice models …

Targeting glucocorticoid receptors: A new avenue for alzheimer's disease therapy

G Canet, N Chevallier, V Perrier, C Desrumaux… - … and therapeutics of …, 2019 - Springer
… memory in relation to increased in the hippocampus region [34]. Chronic mild social stress
or chronic stress-level glucocorticoid administration in 3xTg AD mice triggered the amyloid …

[HTML][HTML] The relationship between stress and Alzheimer's disease

NJ Justice - Neurobiology of stress, 2018 - Elsevier
stress-responsive neurons to alter their function, which in mouse is expressed as elevated
anxiety-related behavior and … mice, we observed a chronic increase in soluble in the CSF …

[HTML][HTML] Chronic stress and glucocorticoids: from neuronal plasticity to neurodegeneration

S Vyas, AJ Rodrigues, JM Silva, F Tronche… - Neural …, 2016 - hindawi.com
… mechanisms through which stress and altered GC levels trigger … high GC levels and/or stress
increase the production of A𝛽 … A later study showed that chronic treatment of 3xTg AD mice

Circadian wheel running behavior is altered in an APP/E4 mouse model of late onset Alzheimer's disease

KN Boggs, PA Kakalec, ML Smith, SN Howell… - … & behavior, 2017 - Elsevier
… that levels of -42, the most toxic species of the protein, … an increase in overall mean
daily activity in the 3xTgAD miceSocial isolation is a stressor in many species, including mice

[HTML][HTML] Targeting psychologic stress signaling pathways in Alzheimer's disease

HS Futch, CL Croft, VQ Truong, EG Krause… - Molecular …, 2017 - Springer
… AD patients have also been found to have altered responses … γ-secretase activity towards
increased production through … behavioral symptoms that accompany chronic stress. Indeed, …

[HTML][HTML] Alcohol as a modifiable risk factor for alzheimer's disease—evidence from experimental studies

DV Chandrashekar, RA Steinberg, D Han… - International Journal of …, 2023 - mdpi.com
normal locomotor activity but altered the spatial memory and cognitive functions in the 3xTg-AD
mice… 145 days, showed an increased cognitive decline, significant increase in and tau …