[PDF][PDF] A double edged sword: Interferon-γ treatment worsens host outcomes in mouse models of pulmonary infection with C. neoformans

J Rudman - 2021 - etheses.whiterose.ac.uk
… There are no two more important people in history, who exemplify everything worth fighting
… infection is critical for host protection during cryptococcosis and understanding how cytokines …

A Fungal Sterylglucosidase at the Intersection of Virulence, Host Immunity, and Therapeutic Development

RA Cramer - Mbio, 2022 - Am Soc Microbiol
… in a murine model of cryptococcosis (13). The SGL1-null … mutant, the ability of live or heat-killed
sglA mutant conidia to … To better define the mechanism of host protection against IA, it will …

[HTML][HTML] Fungal vaccines, mechanism of actions and immunology: A comprehensive review

S Nami, R Mohammadi, M Vakili, K Khezripour… - Biomedicine & …, 2019 - Elsevier
… are related to the fungal infections, cryptococcosis, and … TLR2 gene expression increased
in mice group with systemic … is the heat-killed Saccharomyces cerevisiae (HKS) vaccine, …

A call to arms: quest for a cryptococcal vaccine

MCC Van Dyke, FL Wormley - Trends in microbiology, 2018 - cell.com
Vaccination with heat-killed Cryptococcus mutants … to induce protective immune responses
against cryptococcosisprotection against subsequent Cryptococcus infection in mice. …

Induction of Broad-spectrum Protective Immunity Against Disparate Serotypes of Cryptococcus

MC Van Dyke - 2018 - search.proquest.com
… The murine model of experimental pulmonary cryptococcosisHeat-killed Cryptococcus
mutants remain a viable option and … Cryptococcus vaccine candidate to induce protection against

[HTML][HTML] Vaccines against candidiasis: Status, challenges and emerging opportunity

SR Sahu, S Bose, M Singh, P Kumari… - Frontiers in Cellular …, 2022 - frontiersin.org
… , only three of them protected against invasive candidiasis in mice. Using computational tools,
heat-killed fbp1Δ cross-protected fungal pathogens such as C. neoformans, Cryptococcus

[HTML][HTML] Cryptococcus neoformans Cda1 and Cda2 coordinate deacetylation of chitin during infection to control fungal virulence

R Upadhya, WC Lam, CR Hole, D Parchment, CK Lee… - The Cell Surface, 2021 - Elsevier
… When a cda1Δ strain was tested in a CBA/J mouse model, the … in all three mouse lines, with
the mutant being completely … used as a vaccine either as live cells or in its heat-killed (HK) …

Host populations, challenges, and commercialization of cryptococcal vaccines

M Del Poeta, FL Wormley Jr, X Lin - PLoS Pathogens, 2023 - journals.plos.org
… elicited by heat-killed morphogenesis ZNF2 oe strain, which … protective in various mouse
models of cryptococcal meningitis (… for Host Protection in an Animal Vaccination Model. mBio. …

Promising whole‐cell vaccines against cryptococcosis

K Ueno, S Tsuge, K Shimizu… - Microbiology and …, 2023 - Wiley Online Library
… for host protection in an animal vaccination model. mBio. 2019;10(2). … A heat-killed
Cryptococcus mutant strain induces hostvaccine of Cryptococcus neoformans in a murine model. …

Current trends to control fungal pathogens: exploiting our knowledge in the host-pathogen interaction

LC García-Carnero, LA Pérez-García… - Infection and Drug …, 2018 - Taylor & Francis
… in several fungal infections, such as cryptococcosis, … heat-killed fungal cells, achieved
prolonged survival in mice. … mycosis in an animal model was a conjugate vaccine of GXM…