Progress toward a human vaccine against coccidioidomycosis

GT Cole, BJ Hurtgen, CY Hung - Current fungal infection reports, 2012 - Springer
… same vaccine also provides protection against cryptococcosis [… influence host protection
against this respiratory mycosis are still … of both heat-killed and live vaccines in murine models of …

Fusarium oxysporum as a Multihost Model for the Genetic Dissection of Fungal Virulence in Plants and Mammals

M Ortoneda, J Guarro, MP Madrid… - Infection and …, 2004 - Am Soc Microbiol
… mold causing invasive fungal infections in immunocompromised … heat-killed conidia for testing
their activity in the murine … was induced both by living and heat-killed conidia of the ΔchsV …

Cryptococcal Disease in Diverse Hosts

DB Meya, PR Williamson - New England Journal of Medicine, 2024 - Mass Medical Soc
… to consist of two species complexes, Cryptococcus neoformans … Vaccine-induced immune
responses have been shown in animal models with the use of inactivated cryptococcal mutant

Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4+ T Cells

SG Nanjappa, E Heninger, M Wüthrich… - PLoS …, 2012 - journals.plos.org
… for designing vaccines against fungal infections in immune … in vaccine resistance to lethal
fungal infection in mice rested … ∼2×10 6 CFU of heat-killed vaccine yeast overnight at 37C. On …

[HTML][HTML] American Society for Microbiology

FCWA are Key - Am Soc Microbiol
… in murine models, but seldom have made it to clinical trials. Live-attenuated or heat-killed
whole cell vaccines are methods of vaccination … to effectively protect against cryptococcosis

Vaccine Immunity to Pathogenic Fungi Overcomes the Requirement for CD4 Help in Exogenous Antigen Presentation to CD8+ T Cells: Implications for Vaccine …

M Wüthrich, HI Filutowicz, T Warner… - The Journal of …, 2003 - rupress.org
… + T cells, patients with disseminated cryptococcosis, even with the best … Remarkably, in both
transgenic mouse strains, CD8 + T cells … . Vaccination with heat-killed leishmania antigen or …

Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases

S Levitz, R Wang, L Oliveira, D Lourenco, C Gomez… - 2022 - researchsquare.com
cryptococcal challenge by comparing two mouse strains 87 … IFNɣ release following
stimulation with heat-killed (HK) C. … Required for Host Protection in an Animal Vaccination Model. …

[PDF][PDF] Vaccines for fungal infections

U Tiwari, S Das, M Tandon, VG Ramachandran… - Natl Med J …, 2015 - academia.edu
fungal infections such as Candida and Cryptococcus have … to induce a protective immune
response in a murine model of … antigens in the heat-killed preparation inducing the humoral …

Fungal vaccine development: State of the art and perspectives using Immunoinformatics

MM Inácio, ALE Moreira, VRM Cruz-Leite, K Mattos… - Journal of Fungi, 2023 - mdpi.com
… study, a heat-killed Cryptococcus neoformans Δsgl1 mutant … to induce protective immunity
against cryptococcosis in mice that … vaccines designed to prevent invasive fungal infections are …

Dendritic cell-based vaccine against fungal infection

K Ueno, M Urai, K Ohkouchi, Y Miyazaki… - … : Volume 1: Vaccines for …, 2016 - Springer
vaccine preparation and murine pulmonary infection model … infected with Cryptococcus
neoformans standard strain H99 [7–… (BMDCs) were pulsed with heat-killed C. gattii and were then …