Cytomegalovirus

A Safdar, D Armstrong - Principles and practice of transplant infectious …, 2019 - Springer
… of the CMV viral load in the peripheral blood. A positive … therapy, a genetic drug mutation
analysis should be performed. This is … therapy for CMV retinitis in patients with HIV/AIDS [207]. …

Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments

MK Gandhi, R Khanna - The Lancet infectious diseases, 2004 - thelancet.com
… of human cytomegalovirus in peripheral blood mononuclear cells. … was secondary in need
only to a vaccine for HIV. … At time of cytomegalovirus disease onset, the viral load is higher in R…

[图书][B] Biochemical and virologic analysis of the human cytomegalovirus encoded UL97

CD Shannon-Lowe - 2002 - search.proquest.com
… led to the emergence of ganciclovir resistant strains of HCMV. … to perform longitudinal studies
upon different patient groups at … The median viral loads of HCMV and HIV were determined …

Quantitation of cytomegalovirus: methodologic aspects and clinical applications

M Boeckh, G Boivin - Clinical microbiology reviews, 1998 - Am Soc Microbiol
… at a time when the viral load in their blood is low or not detectable (… of ganciclovir-resistant
CMV isolates from the blood and the … longitudinal molecular analysis of the CMV load and viral

[图书][B] Virologic and immunological studies of human cytomegalovirus in transplant patients

FM Mattes - 2006 - search.proquest.com
… identified maximum virus load and baseline virus load (virus load at … marker than HIV virus
load in the pre-HAART era [23,265]. … of viruses with mutations in the UL97 gene. In the current …

Clinical pharmacokinetic monitoring and resistance testing for the optimisation of antiviral therapy targeting human cytomegalovirus

D Wong - 2022 - unsworks.unsw.edu.au
… novel ganciclovir-resistant mutations examined in this study ....… analysis of a patient specimen
with sufficient viral load. The … with valganciclovir for CMV retinitis in AIDS patients [191]. The …

[PDF][PDF] VIRAL CLASSIFICATION AND BIOLOGY

P PANCHOLI, SI MARTIN - … Manual Fifth Edition/editor in chief …, 2016 - ndl.ethernet.edu.et
… can be used in some ganciclovir-resistant strains of CMV. The … specific for CMV infection;
useful when viral load in blood is … of cytomegalovirus DNA in BAL fluid: a longitudinal study in …

Pathogenesis of human cytomegalovirus in the immunocompromised host

P Griffiths, M Reeves - Nature Reviews Microbiology, 2021 - nature.com
… about serial measures of the viral load to explain features of … an enlarged T cell compartment
dominated by anti-HCMV T … commonly used to treat ganciclovir-resistant strains of HCMV, …

Characterization of human cytomegalovirus genome diversity in immunocompromised hosts by whole-genome sequencing directly from clinical specimens

E Hage, GS Wilkie, S Linnenweber-Held… - The Journal of …, 2017 - academic.oup.com
… For 15 of 20 patients, blood samples obtained longitudinally … of 8 of 15 longitudinally sampled
patients showed mutationsviral loads and high human genomic backgrounds (eg, whole …

Drug-resistant human cytomegalovirus infection in children after allogeneic stem cell transplantation may have different clinical outcomes

T Eckle, L Prix, G Jahn, T Klingebiel… - Blood, The Journal …, 2000 - ashpublications.org
longitudinally for human cytomegalovirus (HCMV) infection … ,9therapy was monitored by
molecular analysis of sequential … the viral load and the detection of further mutations conferring …