… perhexiline maleate and amiodarone, which mainly cause segmental demyelination (…
hormones given to treat possible concomitant hypothyroidism may also exacerbate myasthenia. …

… increase of PAG and concomitant decrease of hippuric acid (… treated with chloroquine,
tamoxifen, quinacrine, perhexiline … drug treatment except for PAG in amiodarone group were not …

… The CYP2D6 drug metabolizing enzyme is susceptible to inhibition by concomitant drugs,
which can lead to a clinical phenotype that is different from the genotype-based phenotype, a …

… , especially in patients with concomitant hepatitis B or C infection. … Drugs such as amiodarone
and perhexiline maleate are … perhexeline maleate or amiodarone can progress even after …

… drugs that produce corneal epithelial changes is amiodarone… In a small case series of patients
with adrenocortical carcinoma (N = … In 1 case related to perhexiline maleate, papilledema (…

… Thus, evaluation of risk factors, such as concomitant use of different potentially myotoxic
drugs, hepatobiliary dysfunction or renal insufficiency, as well as genetic susceptibility in some …

… derangement for concomitant diseases) with concurrent toxic pharmacological treatment (…
some antiarrhythmics and antianginal drugs such as amiodarone and perhexiline) can directly …

… 4,4-DH, perhexiline maleate, and, most recently, amiodarone, … , characterize the injury seen
with these drugs,52,69,97,98 … have been associated with the concomitant use of PB or DPH…

… Patients need to be educated regarding the possible drug interactions of concomitant
drugs and alcohol. Finally, patients who suffer an episode of DILI should be warned to avoid …

… Concomitant … treated with the coronary vasodilator perhexiline, which is no longer widely
used, and is also well documented in patients treated with the antiarrhythmic agent amiodarone…