A Heat-Killed Cryptococcus Mutant Strain Induces Host Protection against Multiple Invasive Mycoses in a Murine Vaccine Model
… protection against Candida albicans. Thus, our data suggest that the heat-killed fbp1Δ strain
… a suitable vaccine candidate against cryptococcosis and other invasive fungal infections in …
… a suitable vaccine candidate against cryptococcosis and other invasive fungal infections in …
Development of a Heat-Killed fbp1 Mutant Strain as a Therapeutic Agent To Treat Invasive Cryptococcus Infection
… for vaccine-induced protection against homologous challenge and … to elicit robust host
protection against cryptococcosis. … Several mutant strains, such as the strain overexpressing the …
protection against cryptococcosis. … Several mutant strains, such as the strain overexpressing the …
Three Models of Vaccination Strategies Against Cryptococcosis in Immunocompromised Hosts Using Heat-Killed Cryptococcus neoformans Δsgl1
TG Normile, M Del Poeta - Frontiers in Immunology, 2022 - frontiersin.org
… agent of cryptococcosis, a life-threatening invasive fungal … conferred complete host protection
to the WT strain even … To assess the longevity of the vaccine-induced host protection, we …
to the WT strain even … To assess the longevity of the vaccine-induced host protection, we …
Immunization with a heat-killed prm1 deletion strain protects the host from Cryptococcus neoformans infection
C Li, Y Meng, H Li, W Du, X Gao, C Suo… - Emerging Microbes & …, 2023 - Taylor & Francis
… The wild-type and mutant strains were heat killed at 99C for 5 min, and supernatants were
… against invasive cryptococcosis, and both Th1 and Th17 immune responses can be induced …
… against invasive cryptococcosis, and both Th1 and Th17 immune responses can be induced …
Protection against Cryptococcosis by Using a Murine Gamma Interferon-Producing Cryptococcus neoformans Strain
FL Wormley Jr, JR Perfect, C Steele… - Infection and …, 2007 - Am Soc Microbiol
… of host immune responses to invasive cryptococcal infection. However, … therapy alone have
failed to induce complete clearance of C. … neoformans strain H99 or H99-γ or heat-killed C. …
failed to induce complete clearance of C. … neoformans strain H99 or H99-γ or heat-killed C. …
… response induced by mucosal immunization with heat-killed Cryptococcus neoformans yeast cells and analysis of a non-human primate model of cryptococcosis
JP McCracken - 2006 - search.proquest.com
… neoformans could be induced by mucosal immunization using a mutant of E. coli heat-labile …
century produced several published clinical cases of cryptococcosis affecting several organs…
century produced several published clinical cases of cryptococcosis affecting several organs…
Immune evasion by Cryptococcus gattii in vaccinated mice coinfected with C. neoformans
MM Hester, D Carlson, JK Lodge, SM Levitz… - Frontiers in …, 2024 - frontiersin.org
… of protection for these strains remains unclear, each induced a … , cryptococcal mutant strain:
Deletion of all three cryptococcal … and the heat-killed WT strain, which are inoculated directly …
Deletion of all three cryptococcal … and the heat-killed WT strain, which are inoculated directly …
Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses
… Cryptococcus neoformans infections are significant causes of morbidity and mortality among
AIDS patients and the third most common invasive … chose to use heat-killed fungi to control …
AIDS patients and the third most common invasive … chose to use heat-killed fungi to control …
Lipid flippase subunit Cdc50 mediates drug resistance and virulence in Cryptococcus neoformans
… Our results showed that all three mutant strains had levels of … strains with YPD, fresh DME,
fresh DME with 10% heat-killed fetal … expression is specifically induced during interaction with …
fresh DME with 10% heat-killed fetal … expression is specifically induced during interaction with …
Dendritic cell-based immunization ameliorates pulmonary infection with highly virulent Cryptococcus gattii
K Ueno, Y Kinjo, Y Okubo, K Aki, M Urai… - Infection and …, 2015 - Am Soc Microbiol
… Cryptococcus neoformans and Cryptococcus gattii causes life-… mutants have been
successfully used as vaccines (29), vaccination using heat-killed R265 or heat-killed Δcap60 strain …
successfully used as vaccines (29), vaccination using heat-killed R265 or heat-killed Δcap60 strain …