… useful method to prevent neurodegeneration in these diseases. In this work, we show that a
highly sulfated CS preparation, CS-E, exerts a neuroprotective effect on neurons treated with …

… A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced
neuronal cell death 高硫酸化コンドロイチン硫酸,CS-Eは,興奮性アミノ酸による神経細胞死を抑制 …

… highly sulfated chondroitin sulfate, CS-E, prevents excitatory amino acid-induced neuronal
cell death … prior to administration of the CS-E preparation, and then examined NMDA-induced …

… negative charged structures that can contribute to reduce local … neurons with a highly
sulfated CS (CS-E) reduced death … neuroprotection in a calcium-overload model of cell death. …

… Chondroitin sulfate E (CS-E), which is characterized by … Preventing deposition of Aβ oligomers
or fibrils is an important … a key role in Aβ-induced cell death. A large number of studies in …

… A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced
neuronal cell death. J Neurochem 2008; 104: 1565-76. [25] Akiyama H, Sakai S, Linhardt …

… Chondroitin sulfates (CS) are a class of sulfated … In particular, low molecular weight CS
reduce cell apoptosis by … 25 parts v/v assay solution (pH 3.0, 1 L), prepared by dissolving 16 mg …

… Ser129 α‑SYN, prevented cell loss and inhibited apoptosis. The subsequent mechanism
study … were exposed to 400 mg/l CS for 24 h, the mitochondria and total protein were prepared …

… production of highly sulfated CS chains, CS-D and CS-E types. … of rat cortical neurons with
CS-E reduced cell death by N-… used to stop production of inhibitory sulfation patterns present …

… the CNS where neuronal cell death and neuroinflammation take … 4-sulfated/6-sulfated ratio
(4s/6s ratio–the ratio between the … on each plate were removed with 1 ml of phenolic solution, …