Glycosaminoglycans and glycomimetics in the central nervous system

D Rowlands, K Sugahara, JCF Kwok - Molecules, 2015 - mdpi.com
… Complementary to this, these CS-E … and neuronal cell death, offers a range of potential
targets for intervention. Glycomimetic strategies that aim to reduce inflammation, encourage cell

Dermatan sulfotransferase Chst14/D4st1, but not chondroitin sulfotransferase Chst11/C4st1, regulates proliferation and neurogenesis of neural progenitor cells

S Bian, N Akyüz, C Bernreuther, G Loers… - Journal of cell …, 2011 - journals.biologists.com
… in sulfation of CS chains, it is possible that chondroitin sulphate proteoglycans (… of highly
sulfated CS-D and CS-E motifs, respectively, resulted in disturbed migration of cortical neurons. …

[HTML][HTML] Isolation and structural characterization of glycosaminoglycans from heads of red salmon (Oncorhynchus nerka)

F Zhang, J Xie, RJ Linhardt - Jacobs journal of biotechnology and …, 2014 - ncbi.nlm.nih.gov
… -GalNAc4S6S were used to prepare a standard curve for chondroitin sulfate analysis. … -derived
mast cells and mucosal mast cells [26]. Since chondroitin sulfate E is highly sulfated, it …

The bright side of the glial scar in CNS repair

A Rolls, R Shechter, M Schwartz - Nature Reviews Neuroscience, 2009 - nature.com
… -borne immune cells, chondroitin sulfate proteoglycans (CSPGs… preventing excitatory amino
acid-induced neuron death 35 . … Sulfated proteoglycan structures have been associated with …

Chondroitin sulfate-derived theranostic nanosystems

M Aquib, DP Wande, PT Kutoka, AM Khamis… - Polymeric …, 2023 - Elsevier
… CS is a sulfated glycosaminoglycan (GAG) composed of … also and was expected to
prevent lung metastasis, which was … , while the prepared nanogel generated a very low-intensity …

The role of glycosaminoglycan motifs in regulating neuronal growth, guidance, and inhibition

VP Swarup - 2014 - search.proquest.com
Chondroitin sulfate (CS) and Heparan sulfate (HS) are the two … of rat cortical neurons with
CS-E reduced cell death by N… efficacy click-xylosides to reduce the glial scar inhibition and …

Dexamethasone administration to the neonatal rat results in neurological dysfunction at the juvenile stage even at low doses

Y Ichinohashi, Y Sato, A Saito, M Ito, K Watanabe… - Early Human …, 2013 - Elsevier
… , has been widely used to prevent the development of a variety of … Neural stem/progenitor
cells prepared from primary … To estimate the extent of cell death in the cultures, we recovered …

Behavioral abnormalities of fetal growth retardation model rats with reduced amounts of brain proteoglycans

A Saito, F Matsui, K Hayashi, K Watanabe… - Experimental …, 2009 - Elsevier
… three brain-specific chondroitin sulfate proteoglycans (CSPGs… of distilled water were added
to this solution. STA 2 -induced … cell density, we examined the extent of apoptotic cell death in …

[HTML][HTML] The important double-edged role of astrocytes in neurovascular unit after ischemic stroke

G Han, L Song, Z Ding, Q Wang, Y Yan… - Frontiers in Aging …, 2022 - frontiersin.org
… , they damage neurons by producing excitatory amino acids, … that EPO can reduce damage
to neurons in vivo and in vitro. … components, especially chondroitin sulfate proteoglycans. …

Perspectives of engineered marine derived polymers for biomedical nanoparticles

K Thi My Tran, T Van Vo, W Duan… - Current …, 2016 - ingentaconnect.com
… A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced
neuronal cell death. J Neurochem 2008; 104: 1565-76. [135] Mizuguchi S, Uyama T, …