… evidence for the expression of a novel calcium-dependent and apamin-insensitive cation-selective
channels that is coexpressed with apamin-sensitive SK-K Ca channels. Because …

… in anterior pituitary cells is not gonadotroph exclusive. … Figure 3C, lower panel, illustrates
the apamin-insensitive I m control … apamin-insensitive outward I m in mouse gonadotrophs is I …

… -go-gene channels (28). Figure 1C illustrates total K v currents in rat pituitary gonadotrophs,
which are … Calcium-activated K + channels (K Ca ) are composed of two families: three small-…

… GnRH into the pituitary portal system … currents, which remained even in the presence of
400 nm apamin (n = 5), may represent apamin-insensitive SK channels or unidentified channels…

… GnRH binds to GnRH receptors on pituitary gonadotrophs and … In the guinea pig study (32),
although SK channel subunit … SK channels or apamin-insensitive K(Ca) channels because …

… The second cell showed periodic single channel activity … we identified as calcium-activated
SK-type potassium channels. By … , pituitary gonadotrophs express relatively few BK channels …

… We find here that 10 μm UCL2077 is extremely effective in blocking nearly all of the
remaining apamin-insensitive component of the sAHP current in GnRH neurons. In hippocampal …

… We have also found that TEA reduces calcium-activated potassium currents in lactotropes
[unpubl… In this study, we have shown that blockers of calcium-activated potassium channels, or …

… remarkably similar to those we describe here in the pancreatic B cell have recently been
demonstrated to evoke rhythmic membrane repolarizations also in pituitary gonadotrophs [24]. …

… that SK1 channels are responsible for the apamin-insensitive currents seen in native tissue.
… ) A novel calciumactivated apamin-insensitive potassium current in pituitary gonadotrophs. …