Noninvasive Metabolomic Profiling of Human Embryo Culture Media Using a Simple Spectroscopy Adjunct to Morphology for Embryo Assessment in in Vitro …

Q Zhao, T Yin, J Peng, Y Zou, J Yang, A Shen… - International journal of …, 2013 - mdpi.com
… the spent culture media of the embryos with lower scores. … embryos were selected based
on the relative concentrations of … the physiology and viability of the pre-implanted embryos [29]…

Relationships between energy metabolism and development of early mammalian embryos

D Rieger - Theriogenology, 1992 - Elsevier
… Financial support for our work on the metabolism of cattle … -book (8), but is intended to draw
attention to the interactions … ) or reduced glutathione (76) is added to the culture medium. The …

Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial

T Hardarson, A Ahlström, L Rogberg… - Human …, 2012 - academic.oup.com
… directly proportional to the concentrations of molecules, such … planned for two embryos to
be transferred, had less than two … Consequently, the results from this study failed to support the …

Culture of one-cell hamster embryos with water soluble vitamins: pantothenate stimulates blastocyst production

SH McKiernan, BD Bavister - Human Reproduction, 2000 - academic.oup.com
culture media, as shown by the relatively low incidence of blastocyst … Culture media that
support normal development and viability … These studies have produced novel media that have …

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

M Murakami, T Ichisaka, M Maeda… - … and cellular biology, 2004 - Taylor & Francis
… in reduced cell size and proliferation arrest in embryonic stem … daily to the culture medium
to final concentrations of 200 nM for … This possibility is supported by the observation that the …

Inhibitors of choline uptake and metabolism cause developmental abnormalities in neurulating mouse embryos

MC Fisher, SH Zeisel, MH Mar, TW Sadler - Teratology, 2001 - Wiley Online Library
Embryonic growth was reduced in embryos treated with … prepare the culture medium. In each
experiment, compounds were … This research was supported by NIH grants HD29495 (TWS) …

Preliminary clinical experience with human blastocyst development in vitro without co-culture

B Behr, TB Pool, AA Milki, D Moore… - Human …, 1999 - academic.oup.com
Low production and accompanying low viability of blastocysts during human IVF as a
manifestation of the inability of any single culture medium to meet the changing nutritionalsupport. …

Insufficient pyruvate in culture medium arrests mouse embryos at the first cleavage stage associated with abnormal epigenetic modifications

P Li, H Zhang, K Yan, L Sui, Y Du, J Hu, H Xu, X Yang… - Theriogenology, 2022 - Elsevier
supporting the first cleavage division of early embryos, we first cultured mouse embryos with
KSOM containing a low … (mKSOM), the pyruvate concentration was reduced to 0.2-fold (0.04 …

[HTML][HTML] Analysis of protein expression (secretome) by human and mouse preimplantation embryos

MG Katz-Jaffe, WB Schoolcraft, DK Gardner - Fertility and sterility, 2006 - Elsevier
… been greatly reduced with the development of culture systems … of spent IVF culture media
but not control media (P<0.05). … low concentrations of proteins secreted by mouse and human …

Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes

N Igosheva, AY Abramov, L Poston, JJ Eckert… - PloS one, 2010 - journals.plos.org
concentrations were similar in obese and lean mice, the … We report that blastocyst development
was reduced in maternal … in the ability to support embryo development to the blastocyst …