[HTML][HTML] A novel peptide antibiotic, Pro10-1D, designed from insect defensin shows antibacterial and anti-inflammatory activities in sepsis models

M Krishnan, J Choi, A Jang, Y Kim - International journal of molecular …, 2020 - mdpi.com
… , novel peptide antibiotics against multidrug-resistant (MDR) … its D-enantiomeric alteration
(Pro10-1D). Among all tested … higher antibacterial as well as anti-biofilm activities than Pro9-…

Antimicrobial peptides conjugated with fatty acids on the side chain of D-amino acid promises antimicrobial potency against multidrug-resistant bacteria

C Zhong, N Zhu, Y Zhu, T Liu, S Gou, J Xie… - European Journal of …, 2020 - Elsevier
… preferable antimicrobial selectivity and anti-biofilm activity. Additionally, the new peptides
also … pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter are …

Antimicrobial and antibiofilm activities of helical antimicrobial peptide sequences incorporating metal-binding motifs

CM Agbale, JK Sarfo, IK Galyuon, SA Juliano… - Biochemistry, 2019 - ACS Publications
… pneumoniae (KpC-Kpn) and multidrug resistant isolates of … synthetic peptides that have
enhanced activity against these … strategy for the generation of potent broad-spectrum AMPs. …

The resilience of Pseudomonas aeruginosa to antibiotics and the designing of antimicrobial peptides to overcome microbial resistance

D Juárez-López, E Morales-Ruiz… - Current Medicinal …, 2023 - ingentaconnect.com
… has triggered the appearance and survival of multidrugresistant (MDR) strains, … potency
[197]; and Antimicrobial Peptide Scanner Vr.2 to predict whether an AMP is active against Gram-…

Potential application of antimicrobial peptides in the treatment of bacterial biofilm infections

N Strempel, J Strehmel… - Current pharmaceutical …, 2015 - ingentaconnect.com
… affirm the potent antibiofilm activity of natural AMPs even in case of infections with
multidrug resistant pathogens, … D-enantiomeric peptides are usually not affected by trypsin-catalyzed …

X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes

S Baeriswyl, BH Gan, TN Siriwardena… - ACS chemical …, 2019 - ACS Publications
aeruginosa as complexes of fucosylated d-enantiomeric … The emergence of multidrug resistant
(MDR) Gram-negative … N-acylated AMPs can also show potent antimicrobial effects. (7,46) …

An overview of antimicrobial peptides and the latest advances in their development

JM Sierra, E Fusté, F Rabanal, T Vinuesa… - Expert opinion on …, 2017 - Taylor & Francis
… In the case of Pseudomonas aeruginosa, it can acquire … antimicrobial peptides (AMPs),
have immunomodulatory … the scarcity of new antibiotics against multidrug-resistant gram-negative …

Kinetics study of antimicrobial peptide, melittin, in simultaneous biofilm degradation and eradication of potent biofilm producing MDR Pseudomonas aeruginosa …

RS Khozani, D Shahbazzadeh… - … Journal of Peptide …, 2019 - search.proquest.com
… and killing potent biofilm producing multidrug-resistant (MDR) P. … anti-biofilm agent is urgently
necessitated. In this regard, we tried to examine the anti-biofilm activity of melittin, a potent

[HTML][HTML] Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds

A Pfalzgraff, K Brandenburg, G Weindl - Frontiers in pharmacology, 2018 - frontiersin.org
… , Acinetobacter baumannii, Pseudomonas aeruginosa, and … antimicrobial peptides due to
their dual-immunomodulatory … for anti-biofilm activity as IK8L, a short synthetic peptide with …

[HTML][HTML] Reprogramming biological peptides to combat infectious diseases

MDT Torres, C de la Fuente-Nunez - Chemical Communications, 2019 - pubs.rsc.org
… agent 6 include DJK-5 (vqwrairvrvir-NH 2 ), a D-enantiomeric … for increasing their antimicrobial
and antibiofilm activities. For … activities against multidrug-resistant bacteria, and most likely …