… burden of fluoride had detrimental genotoxic effects, manifested … fluoride retention in diabetic
rats cause adverse effects not … the margin of safety for fluoride exposure narrowed in these '…

… by which F − exposure might affect glucose-stimulated insulin … to those in urine concentrations
in rats exposed to F − via … the diabetes could increase as the F − exposure increases. …

… in this investigation had caused harmful effects, significant fluoride dose-related differences
would have been expected to occur in some of the blood and/or urine components that serve …

… response, duration of fluoride exposure, and dissolved salts in … SGPT) in diabetic subjects
(owing to the absence/low levels … superoxide radicals into less harmful products like hydrogen …

… are direct adverse effects on the kidneys by excess fluoride, … due to the lack of sufficient
research work on this problem. … of investigations on fluoride toxicity on animals such as rats, mice, …

… Neurological botherations such as lack of muscle … clinical symptoms of chronic fluoride
exposures in humans [35, 46]. … Early toxicity studies in rats have shown fluoride to cause severe …

… the harmful effects of high doses of fluoride on the metabolism and activity of bone tissue. …
and 3 months) and observed that the fluoride exposure increases the expression of osteoblast …

… implicated in atherosclerosis, diabetes, and inflammatory … the absence of the major
antioxidative enzyme SOD, fluoride … , dose and mode of fluoride exposure, time of exposure, and …

… protective potential against fluoride toxicity. Several plant … tract is much higher in absence
of dietary calcium and some … that chronic fluoride exposure is toxic for the diabetic patient …

… able to completely eliminate the free radicals and the other adverse effects generated by
fluoride. … The absence of any significant difference in the level of total protein, compared to the …