Molecular mechanisms of calcium-evoked chloride and bicarbonate secretion from murine airway submucosal gland serous acinar cells

RJ Lee - 2008 - search.proquest.com
fluid secretion mechanisms in airway submucosal gland … similar rates of CFTR-dependent
secretion from intact glands … were used as a source of submucosal gland cells. Previous …

Murine submucosal glands are clonally derived and show a cystic fibrosis gene–dependent distribution pattern

DW Borthwick, JD West, MA Keighren… - … journal of respiratory …, 1999 - atsjournals.org
gland are small cups of cells referred to as a gland acini (19, … of fluid secretions, similar in
role to that found in the sweat … further, we describe a Cftr-dependent distribution pattern. These …

Pathophysiology: epithelial cell biology and ion channel function in the lung, sweat gland and pancreas

RD Coakley, RC Boucher - Cystic fibrosis, 2007 - books.google.com
… from freshly excised CF nasal submucosal glands compared to … of CFTR-dependent
bicarbonate and chloride secretion … of Cl from isotonic liquid secreted in the gland acinus [98]. …

[HTML][HTML] CFTR-rich ionocytes mediate chloride absorption across airway epithelia

L Lei, S Traore, GSR Ibarra, PH Karp… - The Journal of …, 2023 - Am Soc Clin Investig
… -airway epithelia and submucosal glands, thus determining … absorption and CFTR-dependent
liquid secretion. Our … CFTR within the acinus and ducts of the airway epithelium could …

[HTML][HTML] Absent secretion to vasoactive intestinal peptide in cystic fibrosis airway glands

NS Joo, T Irokawa, JV Wu, RC Robbins… - Journal of Biological …, 2002 - ASBMB
… their proximal regions and with serous cells in the distal acini ( … sustained fluid secretion
from pig submucosal glands ( … by HCO 3 − secretion and is CFTR-dependent. Prior studies of […

[HTML][HTML] cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways

RJ Lee, JK Foskett - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
fluid secretion in porcine and human submucosal gland … stimulates fluid secretion by a
CFTR-dependent mechanism … Our results indicate that serous acinar cells secrete fluid by either …

Mechanism of substance P-induced liquid secretion across bronchial epithelium

L Trout, MR Corboz, ST Ballard - American Journal of …, 2001 - journals.physiology.org
… P induces liquid secretion from bronchial submucosal glands … the CFTR-dependent defect
in gland liquid secretion that … and K + currents in airway acinar gland cells by an inositol 1,…

Parasympathetic control of airway submucosal glands: central reflexes and the airway intrinsic nervous system

JJ Wine - Autonomic Neuroscience, 2007 - Elsevier
… secretagogue for fluid secretion from pig and human airway glands, … terminals to their cell
bodies of origin. Thus, to establish the … and CFTR-dependent secretion; this form of secretion is …

Salmeterol restores secretory functions in cystic fibrosis airway submucosal gland serous cells

F Delavoie, M Molinari, M Milliot, JM Zahm… - … journal of respiratory …, 2009 - atsjournals.org
… To demonstrate that the salmeterol effect was a CFTR-dependent mechanism, we showed
that … Acinar origin of CFTR-dependent airway submucosal gland fluid secretion. Am J Physiol …

[HTML][HTML] Protease-activated receptor 2 mediates mucus secretion in the airway submucosal gland

HJ Lee, YM Yang, K Kim, DM Shin, JH Yoon, HJ Cho… - 2012 - journals.plos.org
… anion and fluid secretion in the airway submucosal gland. In … and fluid secretion, the role of
PAR2 in airway mucus secretion … the basolateral side of acinar cells of the submucosal gland. …