Neural Mechanisms of Temporomandibular Joint and Masticatory Muscle Pain

DK Lam - 2008 - library-archives.canada.ca
… review is provided of the trigeminal (V) somatosensory system and pain mechanisms. … root
ganglia at levels C2– C5 all contribute to the nerve fibres in the rat TMJ. Among the autonomic …

[HTML][HTML] Ion channels involved in substance P-mediated nociception and antinociception

CT Chang, BY Jiang, CC Chen - International Journal of Molecular …, 2019 - mdpi.com
… effector systems underlying neurokinin 1 receptors (NK1Rs) in … in rodents produced chronic
and bilateral mechanical … sensory neurons in an autocrine or paracrine manner. In the PNS…

[HTML][HTML] Peripheral and central mechanisms of persistent orofacial pain

M Shinoda, A Kubo, Y Hayashi, K Iwata - Frontiers in Neuroscience, 2019 - frontiersin.org
… 2 receptor pathway following temporomandibular jointtrigeminal nerve injury in rats, and
they are involved in ectopic … that it binds the neurokinin 1 receptor expressed in macrophages, …

Activation of satellite glial cells in the trigeminal ganglion contributes to masseter mechanical allodynia induced by restraint stress in rats

YJ Zhao, Y Liu, YH Zhao, Q Li, M Zhang, YJ Chen - Neuroscience Letters, 2015 - Elsevier
… SGCs were dramatically activated, and substance P (SP) … of conditions involving the
temporomandibular joint (TMJ) … masseter allodynia via an IL-1β paracrine mechanism and …

[HTML][HTML] The role of transient receptor potential (TRP) channels in the transduction of dental pain

MZ Hossain, MM Bakri, F Yahya, H Ando… - International journal of …, 2019 - mdpi.com
mice exhibit a thermal response similar to wild-type mice [100]. … from the facial skin and
temporomandibular joint [105,129,130]… mRNAs for substance P and its receptor neurokinin-1 has …

The role of large-conductance, calcium-activated potassium channels in a rat model of trigeminal neuropathic pain

CY Liu, ZY Lu, N Li, LH Yu, YF Zhao, B Ma - Cephalalgia, 2015 - journals.sagepub.com
… , which could contribute to the mechanical allodynia in the ION-CCI rats. Our … substance P
(SP)) released from the cell body of TG neurons through a paracrine or autocrine mechanism

Oestrogen increases nociception through ERK activation in the trigeminal ganglion: evidence for a peripheral mechanism of allodynia

CS Liverman, JW Brown, R Sandhir, RM Klein… - …, 2009 - journals.sagepub.com
… ERK activation in trigeminal ganglion samples from rats … treatment and inflammation of
the temporomandibular joint. By … local release of substance P (55). TNFα administration into …

The expression of hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1) and HCN2 in the rat trigeminal ganglion, sensory root, and dental pulp

YS Cho, YS Kim, SJ Moozhayil, ES Yang, YC Bae - Neuroscience, 2015 - Elsevier
… and contribute to neuronal excitability and pathological pain. We studied the expression of
HCN1 and HCN2 in the rat trigeminal ganglion (… -activated current in rat dorsal root ganglion

[HTML][HTML] Recent advances in basic research on the trigeminal ganglion

T Goto, SB Oh, M Takeda, M Shinoda, T Sato… - The journal of …, 2016 - Springer
… hybridization (ISH) in rats after rat upper molar extraction. We … from the temporomandibular
joint (TMJ) inflammation by using … that, under TMJ inflammation, substance P (SP) released …

Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats

W Xu, Y Wu, Y Bi, L Tan, Y Gan, KW Wang - Molecular pain, 2010 - journals.sagepub.com
… that central sensitization leads to neuronal hyperexcitability and contributes to … administration
can attenuate the mechanical allodynia of inflamed TMJ, we first … DRG dorsal root ganglion