Cross-talk signaling in the trigeminal ganglion: role of neuropeptides and other mediators

K Messlinger, LK Balcziak, AF Russo - Journal of neural transmission, 2020 - Springer
… of neurokinin-1 (NK1) receptors, receptors for substance P, has indirectly been shown by
functional studies in the rat trigeminal ganglion. … temporomandibular joint and facial skin was …

Neuroimmune interactions in painful TMD: mechanisms and treatment implications

Y Yi, X Zhou, X Xiong, J Wang - Journal of Leukocyte Biology, 2021 - academic.oup.com
… of temporomandibular joint (TMJ), and neurogenic … rat model, TNF-α promotes nociception
in trigeminal ganglia … peptide (CGRP), substance P (SP), and so on, and contribute to local …

Enhanced excitability of nociceptive trigeminal ganglion neurons by satellite glial cytokine following peripheral inflammation

M Takeda, T Tanimoto, J Kadoi, M Nasu, M Takahashi… - Pain, 2007 - Elsevier
… IL-receptor type I (IL-1RI) TRG neurons in inflamed rats was … that temporomandibular joint
(TMJ) inflammation modulates … TMJ inflammation induced up-regulation of NK1 receptors

… receptors to Fos expression in the trigeminal spinal nucleus produced by acute injury to the masseter muscle during persistent temporomandibular joint inflammation …

K Okamoto, A Kimura, T Donishi, H Imbe, Y Nishie… - Neuroscience, 2006 - Elsevier
… al 2005b demonstrated that TMJ inflammation enhanced the … , and the paracrine release of
substance P from TG neurons … receptor activation can enhance the ability of 5-HT3 receptor

Exploring the roles of neuropeptides in trigeminal neuropathic pain: A systematic review and narrative synthesis of animal studies

N Chuinsiri, D Edwards, V Telezhkin, CJ Nile… - Archives of Oral …, 2021 - Elsevier
… Calcitonin gene-related peptide (CGRP) and substance P were … on orofacial mechanical
sensitivity and SP expression in rats. … The paracrine effect of CGRP has been shown on satellite …

Neurobiology of temporomandibular joint pain: therapeutic implications

EA Jennings, MC Williams, V Staikopoulos… - Seminars in …, 2012 - Elsevier
… the dorsal root ganglia (DRG), whereas those of the trigeminal … Importantly, none of these
mice have altered responses after … influx is thought to contribute to the induction of chronic pain. …

Chemokine ligand 2/chemokine receptor 2 signaling in the trigeminal ganglia contributes to inflammatory hyperalgesia in rats

M Takeda, M Nasu, T Kanazawa, M Takahashi… - Neuroscience …, 2018 - Elsevier
… , substance P (SP) and glial-derived neurotrophic factor, act via local paracrine mechanisms
in the sensory ganglia to … of CFA inflammation, suppression of the SP/neurokinin-1 receptor

… of interleukin-1β receptor suppresses the voltage-gated potassium currents in the small-diameter trigeminal ganglion neurons following peripheral inflammation

M Takeda, J Kitagawa, M Takahashi, S Matsumoto - Pain, 2008 - Elsevier
… processes contribute to the mechanism underlying trigeminalTemporomandibular joint
(TMJ) inflammation potentiates the … lower in inflamed rats than in control rats. Together, these …

Painful neuron-microglia interactions in the trigeminal sensory system

AJ Davies, YH Kim, SB Oh - The Open Pain Journal, 2010 - benthamopen.com
substance P from dorsal root ganglion neurons can activatemechanical allodynia and thermal
hyperalgesia in the rat [97]. … of release through a paracrine feedback mechanism. Indeed, …

The role of peripheral NMDA receptors in nerve growth factor-induced muscle pain

HGH Wong - 2015 - open.library.ubc.ca
… -induced mechanical sensitization in the male rats but not in … neck that result in
temporomandibular joint (TMJ) pain and/or … , substance P, and coexpression of NR2B and …