[HTML][HTML] Mechanistic insights into the role of the chemokine CCL2/CCR2 axis in dorsal root ganglia to peripheral inflammation and pain hypersensitivity

…, JM Longpré, S Mélik-Parsadaniantz, P Sarret - Journal of …, 2021 - Springer
… the dorsal root ganglion (DRG) contributes to the peripheral … of substance P back to the level
of sham rats (P < 0.01), while … /or paracrine processes under peripheral chronic inflammation

[HTML][HTML] Mediators of neuropathic pain; focus on spinal microglia, CSF-1, BDNF, CCL21, TNF-α, Wnt ligands, and interleukin 1β

PA Boakye, SJ Tang, PA Smith - Frontiers in Pain Research, 2021 - frontiersin.org
… It acts in a paracrine function to induce rapid inward currents … -knock-out mice lowers
mechanical pain thresholds to levels … to express excitatory substance P receptors after nerve injury…

Neurotrophins: mediators and modulators of pain

S Pezet, SB McMahon - Annu. Rev. Neurosci., 2006 - annualreviews.org
… In dissociated DRG (and trigeminal) neurones, NGF regulates … The neuropeptides substance
P and calcitonin gene-related … the temporomandibular joint of adjuvant arthritic rats Eur. J. …

[HTML][HTML] Satellite glial cells in sensory ganglia: its role in pain

FAL Costa, FL Moreira Neto - Revista brasileira de anestesiologia, 2015 - SciELO Brasil
… in the dorsal root ganglia of rat peripheral neuropathic pain models. Cell Mol … substance P
paracrine mechanism contributes to the mechanical allodynia in the temporomandibular joint

Trigeminal nervous system sensitization by infraorbital nerve injury enhances responses in a migraine model

M Toyama, C Kudo, C Mukai, M Inoue… - …, 2017 - journals.sagepub.com
… reported that temporomandibular joint inflammation increased the content of substance P (…
increased the pERK expression in the trigeminal ganglion of the migraine rat model, it was not …

Pathogenic mechanisms of lipid mediator lysophosphatidic acid in chronic pain

H Ueda - Progress in lipid research, 2021 - Elsevier
… , from the study using mice that are genetically deficient of … an autocrine or paracrine manner
via S1P receptors (S1PR 1… range of inflammatory chemical mediators (substance P/Sub-P

GABAA receptor as a novel regulator of peripheral pain sensitivity and local neuron-glia interaction

V Bonalume - 2020 - air.unimi.it
… vivo model of inflammatory pain on snsCRE:β3-/- mice. The … a complex paracrine mechanism
mediated by SCs, which activate … such as bradykinin, substance P and nerve growth factor (…

[HTML][HTML] Progress in sympathetically mediated pathological pain

SS Chen, JM Zhang - Journal of anesthesia and perioperative …, 2015 - ncbi.nlm.nih.gov
… /or nerve sometimes leads to a chronic pathological pain state, … Activation of these P2X7
receptors can cause further ATP … within the DRG, either through local paracrine actions (77), …

Activation of GABAB receptors potentiates inward rectifying potassium currents in satellite glial cells from rat trigeminal ganglia: in vivo patch-clamp analysis

M Takeda, M Nasu, T Kanazawa, Y Shimazu - Neuroscience, 2015 - Elsevier
… in the trigeminal ganglion (TRG) contributed to trigeminal pain. … messengers, such as ATP,
substance P (SP), calcitonin gene-… 6 in the TRGs after temporomandibular joint inflammation, …

Normalization of neuroinflammation: A new strategy for treatment of persistent pain and memory/emotional deficits in chronic pain

XG Liu - Journal of Inflammation Research, 2022 - Taylor & Francis
… stimuli by substance P, K + and inflammatory mediators … primarily regulated by autocrine
and paracrine, ie, the cytokines … that in rodents with either SNI or L5-SNL, activation of dorsal …