Decanoic acid attenuates the excitability of nociceptive trigeminal primary and secondary neurons associated with hypoalgesia

R Nakajima, A Uehara, S Takehana… - Journal of Pain …, 2018 - Taylor & Francis
… of single TG neurons, the rats underwent a craniotomy and … RN, AU, and ST contributed
equally to this work. All authors … via satellite glial interleukin-1beta paracrine mechanismBrain …

[HTML][HTML] Mediators of neuropathic pain; focus on spinal microglia, CSF-1, BDNF, CCL21, TNF-α, Wnt ligands, and interleukin 1β

PA Boakye, SJ Tang, PA Smith - Frontiers in Pain Research, 2021 - frontiersin.org
… It acts in a paracrine function to induce rapid inward currents … -knock-out mice lowers
mechanical pain thresholds to levels … to express excitatory substance P receptors after nerve injury…

[HTML][HTML] Satellite glial cells in sensory ganglia: its role in pain

FAL Costa, FL Moreira Neto - Revista brasileira de anestesiologia, 2015 - SciELO Brasil
… in the dorsal root ganglia of rat peripheral neuropathic pain models. Cell Mol … substance P
paracrine mechanism contributes to the mechanical allodynia in the temporomandibular joint

GABAA receptor as a novel regulator of peripheral pain sensitivity and local neuron-glia interaction

V Bonalume - 2020 - air.unimi.it
… vivo model of inflammatory pain on snsCRE:β3-/- mice. The … a complex paracrine mechanism
mediated by SCs, which activate … such as bradykinin, substance P and nerve growth factor (…

Trigeminal nervous system sensitization by infraorbital nerve injury enhances responses in a migraine model

M Toyama, C Kudo, C Mukai, M Inoue… - …, 2017 - journals.sagepub.com
… reported that temporomandibular joint inflammation increased the content of substance P (…
increased the pERK expression in the trigeminal ganglion of the migraine rat model, it was not …

Activation of GABAB receptors potentiates inward rectifying potassium currents in satellite glial cells from rat trigeminal ganglia: in vivo patch-clamp analysis

M Takeda, M Nasu, T Kanazawa, Y Shimazu - Neuroscience, 2015 - Elsevier
… in the trigeminal ganglion (TRG) contributed to trigeminal pain. … messengers, such as ATP,
substance P (SP), calcitonin gene-… 6 in the TRGs after temporomandibular joint inflammation, …

Pathogenic mechanisms of lipid mediator lysophosphatidic acid in chronic pain

H Ueda - Progress in lipid research, 2021 - Elsevier
… , from the study using mice that are genetically deficient of … an autocrine or paracrine manner
via S1P receptors (S1PR 1… range of inflammatory chemical mediators (substance P/Sub-P

CGRP and the trigeminal system in migraine

S Iyengar, KW Johnson, MH Ossipov… - … of Head and Face Pain, 2019 - Wiley Online Library
… mediated paracrine signaling can occur within the TG.33 … for neurokinin-1 (NK-1), the
substance P receptor, in … Injecting CGRP into the temporomandibular joint of rats activated

[HTML][HTML] Progress in sympathetically mediated pathological pain

SS Chen, JM Zhang - Journal of anesthesia and perioperative …, 2015 - ncbi.nlm.nih.gov
… /or nerve sometimes leads to a chronic pathological pain state, … Activation of these P2X7
receptors can cause further ATP … within the DRG, either through local paracrine actions (77), …

Normalization of neuroinflammation: A new strategy for treatment of persistent pain and memory/emotional deficits in chronic pain

XG Liu - Journal of Inflammation Research, 2022 - Taylor & Francis
… stimuli by substance P, K + and inflammatory mediators … primarily regulated by autocrine
and paracrine, ie, the cytokines … that in rodents with either SNI or L5-SNL, activation of dorsal …