Regulation of Ubiquitin Mediated Proteolysis of G1 Cyclins and the CDK Inhibitor p27 by the Cullin Gene Family in Normal Tumorigenic Human Breast Cells
J McCarville, Y Xiong… - 2001 - apps.dtic.mil
… enzymes, El (ubiquitin activiating), E2 (ubiquitin conjugating) … modification and assembly of
active CUL1 ubiquitin ligase in the … We suggest that the assembly of active CUL1 ligase is not …
active CUL1 ubiquitin ligase in the … We suggest that the assembly of active CUL1 ligase is not …
[HTML][HTML] Regulation of the G1 to S transition by the ubiquitin pathway
LM DeSalle, M Pagano - FEBS letters, 2001 - Elsevier
… they bind to the ubiquitin-conjugating enzyme Cdc34. SCF Cdc4 … Ubiquitin ligases can be
subdivided based on the cullin … The different complexes can assemble with different E2s as …
subdivided based on the cullin … The different complexes can assemble with different E2s as …
[HTML][HTML] Ectromelia virus BTB/kelch proteins, EVM150 and EVM167, interact with cullin-3-based ubiquitin ligases
BA Wilton, S Campbell, N Van Buuren, R Garneau… - Virology, 2008 - Elsevier
… activated, ubiquitin is transferred to a ubiquitin conjugating … of Roc1, the RING-finger protein
that functions as the ubiquitin … formation of active cullin-3-based ubiquitin ligases potentiality …
that functions as the ubiquitin … formation of active cullin-3-based ubiquitin ligases potentiality …
The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition
D Kang, J Chen, J Wong, G Fang - The Journal of cell biology, 2002 - rupress.org
… of the ubiquitin-conjugating enzymes for the Chfr ligase. An … that Chfr is a ubiquitin ligase
that regulates the activation of the … . Cdc53/cullin and the essential Hrt1 RING-H2 subunit of …
that regulates the activation of the … . Cdc53/cullin and the essential Hrt1 RING-H2 subunit of …
[PDF][PDF] SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation
M Tan, Y Zhao, SJ Kim, M Liu, L Jia, TL Saunders… - Developmental cell, 2011 - cell.com
… SKP1, Cullins, F-box proteins, and a RING protein, RING box … dependent on E2 ubiquitin
conjugating enzyme (Figure 4G). … We further showed in vivo that reduced Ras/Erk activation …
conjugating enzyme (Figure 4G). … We further showed in vivo that reduced Ras/Erk activation …
[PDF][PDF] Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage
H Wang, L Zhai, J Xu, HY Joo, S Jackson… - Molecular cell, 2006 - cell.com
… 1 (DDB1), Cullin 4B, Cullin 4A, damaged DNA binding … histone ubiquitylation, we assembled
mononucleosomes using … cerevisiae ubiquitinconjugating enzymes UBC4 and UBC5 with …
mononucleosomes using … cerevisiae ubiquitinconjugating enzymes UBC4 and UBC5 with …
BTB-Kelch proteins and ubiquitination of kainate receptors
J Marshall, LAC Blair, JD Singer - Kainate Receptors: Novel Signaling …, 2011 - Springer
… Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and
assembly of active ubiquitin ligases by all cullins. J Biol Chem 2002; 277:15758-15765. 42. …
assembly of active ubiquitin ligases by all cullins. J Biol Chem 2002; 277:15758-15765. 42. …
The RING-H2–finger protein APC11 as a target of hydrogen peroxide
… transfer of ubiquitin from a ubiquitin-conjugating enzyme (E2… and mitotic exit, by assembling
multiubiquitin chains on mitotic … We also examined the ubiquitin ligase activity of H 2 O 2 -…
multiubiquitin chains on mitotic … We also examined the ubiquitin ligase activity of H 2 O 2 -…
[PDF][PDF] The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7
AE Tron, T Arai, DM Duda, H Kuwabara, JL Olszewski… - Molecular cell, 2012 - cell.com
… E3 ubiquitin ligases and almost 20 percent of all cellular … ment of the E2 ubiquitin-conjugating
enzyme to the CRL. The … To address if Glmn could bind to a fully assembled CRL, we …
enzyme to the CRL. The … To address if Glmn could bind to a fully assembled CRL, we …
[PDF][PDF] Cloning, characterization and subcellular localization of a gene encoding a human Ubiquitin-conjugating enzyme (E2) homologous to the Arabidopsis thaliana …
G Yin, C Ji, T Wu, Z Shen, X Xu, Y Xie, Y Mao - Front Biosci, 2006 - article.imrpress.com
… is generally through a multienzyme cascade: Firstly, ubiquitin is activated by ubiquitin… by
the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. J Biol Chem. 277…
the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. J Biol Chem. 277…