Regulation of Ubiquitin Mediated Proteolysis of G1 Cyclins and the CDK Inhibitor p27 by the Cullin Gene Family in Normal Tumorigenic Human Breast Cells

J McCarville, Y Xiong… - 2001 - apps.dtic.mil
enzymes, El (ubiquitin activiating), E2 (ubiquitin conjugating) … modification and assembly of
active CUL1 ubiquitin ligase in the … We suggest that the assembly of active CUL1 ligase is not …

[HTML][HTML] Regulation of the G1 to S transition by the ubiquitin pathway

LM DeSalle, M Pagano - FEBS letters, 2001 - Elsevier
… they bind to the ubiquitin-conjugating enzyme Cdc34. SCF Cdc4 … Ubiquitin ligases can be
subdivided based on the cullin … The different complexes can assemble with different E2s as …

[HTML][HTML] Ectromelia virus BTB/kelch proteins, EVM150 and EVM167, interact with cullin-3-based ubiquitin ligases

BA Wilton, S Campbell, N Van Buuren, R Garneau… - Virology, 2008 - Elsevier
activated, ubiquitin is transferred to a ubiquitin conjugating … of Roc1, the RING-finger protein
that functions as the ubiquitin … formation of active cullin-3-based ubiquitin ligases potentiality …

The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition

D Kang, J Chen, J Wong, G Fang - The Journal of cell biology, 2002 - rupress.org
… of the ubiquitin-conjugating enzymes for the Chfr ligase. An … that Chfr is a ubiquitin ligase
that regulates the activation of the … . Cdc53/cullin and the essential Hrt1 RING-H2 subunit of …

[PDF][PDF] SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation

M Tan, Y Zhao, SJ Kim, M Liu, L Jia, TL Saunders… - Developmental cell, 2011 - cell.com
… SKP1, Cullins, F-box proteins, and a RING protein, RING box … dependent on E2 ubiquitin
conjugating enzyme (Figure 4G). … We further showed in vivo that reduced Ras/Erk activation

[PDF][PDF] Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage

H Wang, L Zhai, J Xu, HY Joo, S Jackson… - Molecular cell, 2006 - cell.com
… 1 (DDB1), Cullin 4B, Cullin 4A, damaged DNA binding … histone ubiquitylation, we assembled
mononucleosomes using … cerevisiae ubiquitinconjugating enzymes UBC4 and UBC5 with …

BTB-Kelch proteins and ubiquitination of kainate receptors

J Marshall, LAC Blair, JD Singer - Kainate Receptors: Novel Signaling …, 2011 - Springer
Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and
assembly of active ubiquitin ligases by all cullins. J Biol Chem 2002; 277:15758-15765. 42. …

The RING-H2–finger protein APC11 as a target of hydrogen peroxide

TS Chang, W Jeong, DY Lee, CS Cho… - Free Radical Biology and …, 2004 - Elsevier
… transfer of ubiquitin from a ubiquitin-conjugating enzyme (E2… and mitotic exit, by assembling
multiubiquitin chains on mitotic … We also examined the ubiquitin ligase activity of H 2 O 2 -…

[PDF][PDF] The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7

AE Tron, T Arai, DM Duda, H Kuwabara, JL Olszewski… - Molecular cell, 2012 - cell.com
… E3 ubiquitin ligases and almost 20 percent of all cellular … ment of the E2 ubiquitin-conjugating
enzyme to the CRL. The … To address if Glmn could bind to a fully assembled CRL, we …

[PDF][PDF] Cloning, characterization and subcellular localization of a gene encoding a human Ubiquitin-conjugating enzyme (E2) homologous to the Arabidopsis thaliana …

G Yin, C Ji, T Wu, Z Shen, X Xu, Y Xie, Y Mao - Front Biosci, 2006 - article.imrpress.com
… is generally through a multienzyme cascade: Firstly, ubiquitin is activated by ubiquitin… by
the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. J Biol Chem. 277…