IAP family proteins—suppressors of apoptosis
QL Deveraux, JC Reed - Genes & development, 1999 - genesdev.cshlp.org
… heterotetrameric protease. In mammalian cells, activation of the caspase zymogens has …
by granzyme B, an aspartate-specific serine protease found in the granules of cytolytic T-cells; …
by granzyme B, an aspartate-specific serine protease found in the granules of cytolytic T-cells; …
Endolysosomal proteases and their inhibitors in immunity
PI Bird, JA Trapani, JA Villadangos - Nature Reviews Immunology, 2009 - nature.com
… factor that has strict protease specificity for immunoglobulins … and granulocytes contain
numerous serine proteases that … of proteases released into the cytoplasm reaches an activation …
numerous serine proteases that … of proteases released into the cytoplasm reaches an activation …
Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model
D Garwicz, A Lennartsson, SE Jacobsen… - …, 2005 - haematologica.org
… involvement during inflammation, the neutrophil serine proteases have other important …
Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. Biochem J …
Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. Biochem J …
Apoptotic pathways: involvement of lysosomal proteases
… Caspase activation, which requires proteolytic processing at … The only other protease with
the same P1 specificity is the … The last one mentioned here is the serine protease cathepsin …
the same P1 specificity is the … The last one mentioned here is the serine protease cathepsin …
Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice
LA Pennacchio, DM Bouley, KM Higgins, MP Scott… - Nature …, 1998 - nature.com
… -specific proteases are capable of this activation. For instance, the serine protease cathepsin
G can activate … For instance, the aqueous layer of normal tear film contains serine proteases …
G can activate … For instance, the aqueous layer of normal tear film contains serine proteases …
SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G
M Baumann, CTN Pham… - Blood, The Journal of the …, 2013 - ashpublications.org
… cytotoxic function for the serine protease CG and showed that … activation of caspases. In
addition, PMNs carry a unique set of … specificity for chymotrypsin-like and elastase-like serine …
addition, PMNs carry a unique set of … specificity for chymotrypsin-like and elastase-like serine …
Expression of serine protease inhibitor 3 in ocular tissues in endotoxin-induced uveitis in rat
A Takamiya, M Takeda, A Yoshida… - … & visual science, 2001 - iovs.arvojournals.org
… The serine protease inhibitor (SPI) family includes genes in … SPI-3 is induced in specific cells
of the ocular tissues in response … a proteolytic insult caused by excessively activated serine …
of the ocular tissues in response … a proteolytic insult caused by excessively activated serine …
Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways
EC Vaquero, M Edderkaoui, KJ Nam, I Gukovsky… - Gastroenterology, 2003 - Elsevier
… of which involve activation of specific cysteine proteases, the caspases. One is triggered by
clustering and activation of the “… Similar protection has been observed in other cell types.18 …
clustering and activation of the “… Similar protection has been observed in other cell types.18 …
Procaspase-3 activation by a metalloprotease secreted from Vibrio vulnificus
HY Kim, AK Chang, JE Park… - International …, 2007 - spandidos-publications.com
… vulnificus, ATCC 29307, which we named vEP, is a broad specificity enzyme that activates
… GS: Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. …
… GS: Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. …
Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo
JP Galvin, LHA Spaeny-Dekking, B Wang… - The Journal of …, 1999 - journals.aai.org
… However, the cationic nature of the serine protease may lead to nonspecific interactions with
both … . Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. …
both … . Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. …