[HTML][HTML] Investigation of anxiety-and depressive-like symptoms in 4-and 8-month-old male triple transgenic mouse models of Alzheimer's disease
D Várkonyi, B Török, E Sipos, CL Fazekas… - International Journal of …, 2022 - mdpi.com
… investigate whether the triple-transgenic mouse (3xTg-AD) is … , the locomotor activity of the
3xTg-AD mice and controls did … animals compared to control, supporting age-related decline. …
3xTg-AD mice and controls did … animals compared to control, supporting age-related decline. …
Primary and secondary signatures of psychomotor dysfunction in experimental models of normal aging and Alzheimer's disease
LE Castillo Mariqueo - 2022 - tdx.cat
… Alzheimer's disease (AD) is an age-related progressive … The triple transgenic 3xTg-AD
mouse model was first described in … in the exploratory activity of the 3xTg-AD mouse model and …
mouse model was first described in … in the exploratory activity of the 3xTg-AD mouse model and …
[HTML][HTML] … therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´ s disease
JM Muñoz-Cabrera, AG Sandoval-Hernández, A Niño… - PLoS …, 2019 - journals.plos.org
… model of Alzheimers disease … changes in very old triple transgenic AD mice (3xTg-AD mice).
… The activity recorded with the microelectrode in CA1 was magnified 100 times using an AC-…
… The activity recorded with the microelectrode in CA1 was magnified 100 times using an AC-…
Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD)
… activity was reduced in forebrain samples of 3xTg-AD mutants relative to non-transgenic …
had continuous access to food and water in a temperature-controlled room (22 C) under natural …
had continuous access to food and water in a temperature-controlled room (22 C) under natural …
Locomotor behaviour, emotionality, and cognition in the 3xTg-AD mouse model of Alzheimer's disease: A cross-sectional study
LM Fraser - 2013 - dalspace.library.dal.ca
… Neuropathology of 3xTg-AD Mice Triple transgenic mice were … for the 3xTg-AD mice (and
were used to create the control strain in the present study) have different patterns of agerelated …
were used to create the control strain in the present study) have different patterns of agerelated …
Disruption of metabolic, sleep, and sensorimotor functional outcomes in a female transgenic mouse model of Alzheimer's disease
DC Nwafor, S Chakraborty, S Jun, AL Brichacek… - Behavioural brain …, 2021 - Elsevier
… /heat (kcal/hr), sleep profiles, and locomotor activity as described … CVN-AD mice had a
significantly decreased activity in the … + regulatory T cells in a 3xTg-AD Alzheimer's disease model …
significantly decreased activity in the … + regulatory T cells in a 3xTg-AD Alzheimer's disease model …
[HTML][HTML] Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice
D Arsenault, C Tremblay, V Emond, F Calon - Biology of sex Differences, 2020 - Springer
… The triple-transgenic model of AD (3xTg-AD) displays Aβ … These transgenic mice develop
an age-related progressive … In agreement with the higher firing activity found in 3xTg-AD …
an age-related progressive … In agreement with the higher firing activity found in 3xTg-AD …
… -dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic …
C Dias, CF Lourenço, E Ferreiro, RM Barbosa… - Neurobiology of …, 2016 - Elsevier
… Using the triple transgenic mouse model of AD (3xTgAD), we … mouse model of AD to
explore AD- and age-related … synaptic activity with changes in • NO concentration dynamics. …
explore AD- and age-related … synaptic activity with changes in • NO concentration dynamics. …
Regional hypometabolism in the 3xTg mouse model of Alzheimer's disease
A Adlimoghaddam, WM Snow, G Stortz, C Perez… - … of disease, 2019 - Elsevier
… Alzheimer's disease (AD) is a progressive age-related … this factor, brain metabolic activity
in 3xTg-AD mice and age-… -PET neuroimaging to a triple transgenic AD mouse (3xTg), which …
in 3xTg-AD mice and age-… -PET neuroimaging to a triple transgenic AD mouse (3xTg), which …
[HTML][HTML] Cognitive impairment in the 3xTg-AD mouse model of Alzheimer's disease is affected by Aβ-immunotherapy and cognitive stimulation
AR Roda, G Esquerda-Canals, J Martí-Clúa, S Villegas - Pharmaceutics, 2020 - mdpi.com
… early occur in triple-transgenic (3xTg-AD) mice. Specifically, … Furthermore, other age-related,
protective or disease-… However, 3xTg-AD mice always exhibited less activity than NTg mice. …
protective or disease-… However, 3xTg-AD mice always exhibited less activity than NTg mice. …