… a role in cognitive symptoms of Alzheimer's disease (AD). … is consistent with an age-related
progressive loss of PAK (Fig… 3xTg-AD mice are dependent of PAK activity, we crossed the …

… Alzheimer's disease (AD) is a devastating age-related neurodegenerative disease with no
… Melatonin treatment did not affect the running activity of the mice after the first 2 weeks of …

… activity was reduced in forebrain samples of 3xTg-AD mutants relative to non-transgenic …
had continuous access to food and water in a temperature-controlled room (22 C) under natural …

… Alzheimer’s disease (AD) is the leading cause of age-related … In the triple transgenic AD
mouse model (3xTg-AD), … not affect general motor activity of 3xTg-AD mice during Novel Object …

… autonomic and behavioral changes such as malaise, decreased activity, diminished social
… Some age-related processes have been linked to Aβ aggregation as age-related neuronal …

… , Vector Laboratories) at room temperature on a shaker for 15 … brain and body resulting from
chronic overactivity or underactivity … -related pathologies in male tripletransgenic mice. BMC …

… in the female triple transgenic Alzheimer’s (3xTgAD) mice and … an age-related decrease
in brain glucose uptake in 3xTgAD … Hexokinase activity in 3xTgAD hippocampus decreased …

… Already in 3-month-old 3xTg-AD mice, we detected a … Here we compare the age-related
changes with changes … This may indicate a reduced transcriptional activity in one …

… triple-transgenic mouse model of human AD (3xTgAD), which … to block endogenous peroxidase
activity. Using Vectastain … not show any age-related change in cognitive performance for …

… and agerelated diseases such as neurodegenerative disorders [7]… animal conditions for
pathogens, temperature (22 ± 2 … in NK activity exerted by the EE exposure of the mice, achieving …