… some propose that detailed histological subtyping with established … increased risk of
secondary malignancy (particularly leukemia and … Aggressive prolactin-secreting pituitary tumors …

… aggressive tumors warranting more intensive management and … and histological assessments
of aggressiveness found ‘… prolactin normalisation and tumor necrosis but without tumor …

… pituitary adenomas are typical with monotonous histological … and treatment of patients with
aggressive pituitary adenomas … Pituitary adenomas that produce GH, prolactin, ACTH or TSH …

… of aggressiveness and refractoriness to conservative treatment … of an invasive PA with
histological markers of cell proliferation … in tumor volume with a normalization of serum prolactin …

… pathology marker was available for 97 aggressive pituitary … In a subset of patients, prolactin
levels may be normalised … both in aggressive pituitary tumours and other malignancies with …

… same histological evaluation as the primary pituitary tumor. … prolactin levels and tumor size
despite prior surgery, medical … successful development of new cancer therapies. Subsequently…

… tumors, the precise diagnosis is made by pathologic … is not successful or if the tumor exhibits
aggressive behavior, eg, … Pergolide for the treatment of pituitary tumors secreting prolactin …

… pathological characteristics and treatment outcomes in a large cohort of aggressive pituitary
tumours (APT)/pituitary … was 46 years (range 3–74 years); 32% of the tumours were prolactin …

… of transplantable spontaneous prolactin tumors, grafted in … These results indicated that
pathological markers might help … Early diagnosis and specific treatment of aggressive tumors …

… each pituitary tumor in our collection were embedded in paraffin for pathological diagnosis
… For q-RTPCR, total RNA was subjected to DNase treatment using an RNeasy minikit (Qiagen…