… alter the levels and distribution of chromatin modifications throughout the nucleus and at
aging-associated … acid synthesis protein 5; HDAC1, histone deacetylase 1; HGPS, Hutchison-…

… We focus on histone acetylation, which is typically associated … Since it is known that the
cell cycle is altered during … Both KAT6A and KAT6B have been shown to associate with …

… acetyltransferase 6B (KAT6B), is a histone acetyltransferase … the expression of KAT6B was
significantly decreased in HCC… Therefore, we speculate that KAT6B has a closer relation with …

… , histone acetyltransferase (HATs) and histone deacetylases (… surrounding a tumor already
changed a lot in transcriptional … Epigenetics of aging and agingassociated diseases. Int J …

… the innate response, due in part to altered production and function … a selective advantage
for aged hematopoietic stem cells (HSC), … of the histone acetyltransferase Kat6b or the histone …

… that influence hematopoietic stem and progenitor cell (HSPC) fate. … of a histone
acetyltransferase and epigenetic regulator, Kat6b, … of the HSC compartment, and altered …

… showed expanded hematopoietic stem and progenitor cells (… to histone tails by enzymes
called histone acetyltransferases (… A paralogue of MOZ, KAT6B, was recently shown to regulate …

… , with functional decline impacting … -related deficiencies in hematopoietic stem cells [HSCs],
which reside in the bone marrow and differentiate throughout life to give rise to mature cells …

… Histone acetylation is the enzymatic addition of an acetyl group … (KAT2B, KAT3A, KAT3B,
and KAT6B) expression was … ), leading to aging-associated changes. Increasing methylation of …