[HTML][HTML] Proinsulin C-peptide prevents impaired wound healing by activating angiogenesis in diabetes

YC Lim, MP Bhatt, MH Kwon, D Park, SH Na… - Journal of Investigative …, 2015 - Elsevier
wound repair and leads to the development of chronic … of vascular angiogenesis through
the activation of ERK1/2, Akt, … The most important finding of the present study is that C-peptide–…

[HTML][HTML] … derived from human bone marrow mesenchymal stem cells stimulated by deferoxamine accelerate cutaneous wound healing by promoting angiogenesis

J Ding, X Wang, B Chen, J Zhang… - BioMed research …, 2019 - ncbi.nlm.nih.gov
… determination of blood vessel density in the wound sites on … implicated for miR-126 in
development of vascular tissues [26]. … PI3K/AKT pathway and enhance skin wound recovery in the …

Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis

J Jacobi, BYY Tam, U Sundram, G Degenfeld, HM Blau… - Gene therapy, 2004 - nature.com
vascular endothelial growth factor (VEGF) have been identified to play an essential role
in vascular development… of p-Akt, we performed immunohistochemical staining for p-Akt. …

… regulation of the VEGF signaling path and tissue vascularization: Hydrogen peroxide, the common link between physical exercise and cutaneous wound healing

S Roy, S Khanna, CK Sen - Free radical biology and medicine, 2008 - Elsevier
… to be similar to blood vessel development or angiogenesis. … associated disorders such as
wound healing, lymphedema, and … is essential for embryonic cardiovascular development. …

Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

H Nosrati, R Aramideh Khouy, A Nosrati… - Journal of …, 2021 - Springer
… of vessels, causes vascular maturation, and keeps integrity … by activation of Akt and protein
kinase B through the P13K … membrane for vascular regeneration in wound healing [106]. …

Overexpressing IRS1 in endothelial cells enhances angioblast differentiation and wound healing in diabetes and insulin resistance

S Katagiri, K Park, Y Maeda, TN Rao, M Khamaisi… - Diabetes, 2016 - Am Diabetes Assoc
… be the result of decreased vascular endothelial growth factor (… VEGF expression mostly
through the IRS1/PI3K/Akt pathway, … and angiogenesis in cutaneous wound healing (25–27). The …

Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix

J Li, YP Zhang, RS Kirsner - Microscopy research and …, 2003 - Wiley Online Library
essential for wound repair. Migration of endothelial cells and development of new capillary
vessels during wound repair … v beta 3 on vascular cells during wound repair. Am J Pathol 148:…

[PDF][PDF] The role of insulin in wound healing process: mechanism of action and pharmaceutical applications

DH Abdelkader, MA Osman… - Journal of Analytical …, 2016 - sure.sunderland.ac.uk
… that Akt activation is an important step for VEGF release in skin wounds, through a post-…
in keratinocytes [24,25], and is necessary for vascular maturation and angiogenesis during

Modelling skin wound healing angiogenesis: A review

A Guerra, J Belinha, RN Jorge - Journal of theoretical biology, 2018 - Elsevier
blood vessel network through angiogenesis is an essential … models of wound healing
angiogenesis are reviewed in the … Accordingly, the development of higher dimension models …

Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways

T Yi, SG Cho, Z Yi, X Pang, M Rodriguez, Y Wang… - Molecular cancer …, 2008 - AACR
… Thymoquinone inhibited vascular endothelial growth factor–… no inhibitory effects on
vascular endothelial growth factor … important step of angiogenesis (26), we did wound-healing