… J tolerates the amiodarone well and reports no difficulty breathing. He remains … quinidine,
procainamide has few anticholinergic effects and does not alter plasma levels of digoxin…

… , dofetilide does not appear to interact with digoxin, propranolol… of the effects of many
drugs—such as quinidine, propafenone… characteristics of amiodarone is that despite its effect on …

… Both cyclosporin and quinidine are modulators of P-glycoprotein… in 0.9% NaCl (cyclosporin,
verapamil and quinidine) or DMSO (… Amiodarone and nifedipine, two other drugs reported to …

… For amiodarone, the active metabolite desethyl-amiodarone … concentration-effect curves,
as suggested for digoxin[76]and … Quinidine is bound to α 1 -acid glycoprotein, and the binding …

… digoxin when quinidine is coadministered reflects this action in vivo, particularly since the
effects of quinidine (increased digoxin … digoxin concentrations (eg, amiodarone, verapamil, …

… Block which does not depend on repetitive stimulation (or channel activation). If the drug binds
to … is scaled down without change of the time course. If the drug affinity for the rested state …

… with verapamil, quinidine is a relatively safe and effective alternative to sotalol and amiodarone
… Previous experiences with quinidine often involved the use of digoxin. Four of the 6 trials …

… The common risk factors for digoxin toxicity are impaired renal function, advanced age and
… inhibitors (amiodarone, verapamil, quinidine and ciclosporin) can increase serum digoxin …

… the known clinical interaction of digoxin with drugs such as verapamil, quinidine and
amiodarone, which are effective … Amiodarone increases plasma digoxin concentrations. Br. Med. …

… of digitalis and adenosine are discussed later in this chapter. … is an amiodarone analog without
iodine in its structure; it is … in overdose, it can cause “quinidine-like” effects similar to those …